TLDR Biotin treatment improved hair and skin issues in a child with biotinidase deficiency.
Biotinidase deficiency, an autosomal recessive disorder affecting biotin metabolism, was associated with dermatological symptoms such as alopecia, periorificial dermatitis, and seborrhoeic dermatitis. In a case study of a 6-year-old male patient exhibiting periorificial lesions, alopecia, and microscopic hair shaft defects, clinical signs improved significantly with biotin treatment.
50 citations
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March 1992 in “PubMed” Malnutrition causes skin changes due to nutrient deficiencies.
72 citations
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October 1988 in “Archives of Disease in Childhood” Biotin treatment improves symptoms of biotinidase deficiency, but some neurological damage may be permanent.
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January 2015 in “Current problems in dermatology” Ultraviolet rays damage hair, smoking may cause hair loss, and good nutrition is important for hair health, but genetics mainly decide hair thickness.
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March 2020 in “PubMed” Biotin deficiency is not a major cause of Telogen Effluvium hair loss.
November 2019 in “Harper's Textbook of Pediatric Dermatology” Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.
November 2019 in “Harper's Textbook of Pediatric Dermatology” The document is a detailed medical reference on skin and genetic disorders.
March 2000 in “Preventive Nutrition and Food Science” Whalgichan improved hair growth, reduced hair loss, and enhanced cholesterol and lipid metabolism without side effects.
