August 2024 in “Archives of Dermatological Research” This study found that individuals with early-onset androgenetic alopecia showed significant differences in metabolic parameters compared to those with normal-onset alopecia, suggesting a potential link between androgenetic alopecia and metabolic syndrome. However, the nature of this relationship remains uncertain.
June 2024 in “Research Square (Research Square)” In this cross-sectional study, researchers observed that individuals with early-onset androgenetic alopecia showed significant differences in hair growth parameters and metabolic factors compared to those with normal-onset AGA, suggesting a potential association with metabolic syndrome, though more research is needed to clarify this relationship.
53 citations
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April 2016 in “PubMed” This review discusses the relationship between PCOS and hirsutism, exploring inflammatory markers and treatment options, and concludes that combining metformin with OCP may benefit both normal weight and obese PCOS patients.
September 2024 in “Journal of the American Academy of Dermatology” In this prospective study, researchers observed that early-onset androgenetic alopecia may predispose young male patients to metabolic syndrome, as significant differences in metabolic profiles were found between these patients and age-matched controls.
December 2022 in “PubMed” This study observed that one-third of men with early-onset androgenetic alopecia had altered hormonal profiles, which were associated with increased insulin resistance and more severe hair loss.
6 citations
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October 2010 in “Gynecological Endocrinology” This study found that relatives of women with symptoms of oligo-amenorrhoea and hirsutism experienced higher rates of hirsutism, menstrual disorders, infertility, childlessness, diabetes, and hypertension compared to relatives of symptomless women.
May 2024 in “Journal of cosmetic dermatology” This study found that early-onset male androgenetic alopecia is associated with abnormal lipid metabolism and lower levels of certain serum markers, which may serve as risk factors or protective factors for the condition.
January 2026 in “RSC Advances” This study used a zebrafish model and advanced mass spectrometry to identify 11 metabolites of epristeride, revealing significant effects on purine metabolism and aromatic amino acid biosynthesis, which may aid in developing anti-doping detection methods.
91 citations
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July 2022 in “Frontiers in Endocrinology” This study reported that Chinese women with PCOS exhibited diverse lipid profiles based on different characteristics, which may help understand their increased risk of cardiovascular disease.
3 citations
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January 2022 in “Anais Brasileiros De Dermatologia” This study suggests that pediatric androgenetic alopecia is often associated with metabolic syndrome risk factors, highlighting the importance of early diagnosis for potential future health complications.
7 citations
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January 2017 in “Journal of South Asian Federation of Obstetrics and Gynaecology” This study found that 45.8% of women with polycystic ovarian syndrome in the reproductive age group had metabolic syndrome, with low HDL and high triglycerides being significant characteristics.
July 2022 in “British Journal of Dermatology” July 2022 in “British Journal of Dermatology”
May 2023 in “Research Square (Research Square)” This study identified 18 significant metabolites and two enriched metabolic pathways, necroptosis and ABC transporters, in serum samples of acne patients with and without insulin resistance, potentially aiding in the clinical diagnosis and drug development for these patients.
21 citations
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November 2015 in “Archives of Gynecology and Obstetrics” Greek women with PCOS have a higher risk of metabolic syndrome and are more likely to be overweight compared to healthy controls.
May 2025 in “Nutrition and Diabetes” This study found that elevated 1-hour plasma glucose in women with PCOS was associated with increased risk of metabolic disorders and gestational diabetes, indicating it may be a useful marker for adverse metabolic status.
1 citations
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January 2016 in “International journal of reproduction, contraception, obstetrics and gynecology” This study found that hypothyroidism in women with PCOS significantly increased insulin resistance and obesity, which might worsen metabolic issues and impact conditions like hair loss and infertility.
31 citations
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January 2014 in “Clinical Endocrinology” This study found no significant differences in metabolic characteristics between different phenotypes of PCOS or between women with PCOS and healthy controls among reproductive-aged Iranian women.
This study protocol aims to explore the prevalence of polycystic ovary syndrome among female pediatric patients with spina bifida, focusing on metabolic and phenotypic differences, but reports no new results yet.
June 2012 in “Springer eBooks” Eating disorders can cause various hair problems, and while hair loss in these disorders is linked to metabolic syndrome, treatment focuses on specific medications and lifestyle changes for the syndrome.
15 citations
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January 2015 in “Clinical and Experimental Reproductive Medicine” This study reports that obesity significantly influences cardiovascular and metabolic disturbances in women with PCOS, with overweight women experiencing more severe symptoms compared to their non-obese counterparts.
September 2018 in “Journal of the American Academy of Dermatology” Elderly patients with CCCA were all African American with low vitamin D, but no iron or zinc deficiencies, and no hormonal imbalances compared to younger patients.
15 citations
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October 2019 in “BMJ Open” This protocol outlines a nationwide study to investigate the prevalence of metabolic and reproductive abnormalities, anxiety, and depression in Brazilian women with polycystic ovary syndrome, aiming to inform public health strategies.
7 citations
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September 2024 in “Applied Microbiology and Biotechnology” In this study, researchers observed that Malassezia species show different lipid metabolism and growth patterns depending on pH, with slightly acidic conditions promoting beneficial lipid bio-conversion for skin health, while neutral pH resulted in lower growth and lipid content, potentially negatively impacting the skin.
32 citations
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June 2019 in “Frontiers in Endocrinology” This review discusses the overlapping clinical features and diagnostic challenges of non-classic adrenal hyperplasia and polycystic ovary syndrome without presenting original research findings.
5 citations
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January 2017 in “Acta Endocrinologica” This case report discusses a postmenopausal woman whose hyperandrogenism and metabolic symptoms improved significantly after the surgical removal of an ovarian Leydig cell tumor, confirmed post-operatively.
This study found that in men with androgenetic alopecia, elevated triglycerides were the only factor consistently associated with the condition, suggesting a potential link between AGA and lipid metabolism, although other hormonal, metabolic, and sleep factors were not significantly different after propensity score matching.
April 2021 in “Medical Science and Discovery” This study found that men with early androgenetic alopecia had higher levels of free testosterone, DHEAS, and LH, along with insulin resistance and higher homocysteine levels, suggesting they share risk profiles similar to PCOS in women.
258 citations
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July 2016 in “Reproductive Biology and Endocrinology” This abstract reviews the characteristics and health risks associated with polycystic ovary syndrome and does not report new findings, highlighting the syndrome's multifactorial nature.
29 citations
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March 2015 in “Clinical Endocrinology” This study found that women with polycystic ovary syndrome in the UK show significant differences in phenotypic and metabolic characteristics based on ethnicity, age, and obesity, influencing management strategies.