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PCOS treatment focuses on lifestyle changes and specific medications to manage symptoms and complications.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Melatonin makes cashmere grow earlier and more by increasing certain gene activity in goats.

Testosterone reduces heart damage and inflammation after injury.

The document concludes that managing PCOS requires a comprehensive approach, including lifestyle changes and medication, to improve symptoms and reduce health risks.

Menopause can cause hair thinning and texture changes due to hormonal and metabolic shifts.

Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.

OsPRX83 helps rice survive stress by improving stress response and antioxidant activity.

The scalp fat tissue of men with hair loss shows changes in gene activity that may contribute to their condition.

Light therapy may improve eye conditions by stimulating cell activity and increasing oxygen availability.

Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.

The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

High ornithine decarboxylase levels may lead to hair loss and cancer by increasing CK2 activity in the nucleus.

Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.

Obesity is common in PCOS patients and early treatment is important for their heart and metabolic health.

Excess androgens may cause PCOS, not just be a symptom.

Ethnicity affects how polycystic ovary syndrome shows up in women, with white women having higher metabolic risks but less diabetes, and South Asian women showing more androgenic symptoms and being younger at presentation.

Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Acne patients have higher levels of mTOR in their skin, which could be linked to future metabolic disease.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

The document concludes that more research is needed to understand how to treat muscle pain with drugs.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

More PDCD4 is linked to obesity, insulin problems, and cell death in ovaries for those with polycystic ovary syndrome.

CXXC5 is a protein that controls cell growth and healing processes, and changes in its activity can lead to diseases like cancer and hair loss.

Annurca apple extract promotes hair growth by changing hair follicle metabolism to boost keratin production.

New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.

Changing the diet of mice lacking the enzyme CBS can affect symptoms related to the genetic condition.