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Obesity is common in PCOS patients and early treatment is important for their heart and metabolic health.

Excess androgens may cause PCOS, not just be a symptom.

Ethnicity affects how polycystic ovary syndrome shows up in women, with white women having higher metabolic risks but less diabetes, and South Asian women showing more androgenic symptoms and being younger at presentation.

Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Acne patients have higher levels of mTOR in their skin, which could be linked to future metabolic disease.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

The document concludes that more research is needed to understand how to treat muscle pain with drugs.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

More PDCD4 is linked to obesity, insulin problems, and cell death in ovaries for those with polycystic ovary syndrome.

CXXC5 is a protein that controls cell growth and healing processes, and changes in its activity can lead to diseases like cancer and hair loss.

Annurca apple extract promotes hair growth by changing hair follicle metabolism to boost keratin production.

New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.

Changing the diet of mice lacking the enzyme CBS can affect symptoms related to the genetic condition.

Eating a high-fat fish oil diet caused mice to lose hair due to a specific immune cell activity in the skin linked to a protein called E-FABP.

Ishige sinicola extract helps bone-building cells grow and mature, which could aid in treating osteoporosis.

Hair loss causes differ between men and women due to changes in hormone levels and inflammation-related pathways.

Treating hidradenitis suppurativa needs long-term care and teamwork among doctors, but there's a lack of strong guidance on how to do it.

Small hormonal imbalances can cause significant health problems, so more sensitive testing for hormone-disrupting chemicals is needed.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Metformin may help regulate periods and cause modest weight loss in PCOS patients, but more research is needed.

PCOS is a hormonal disorder causing symptoms like irregular periods and acne, and increases the risk of diabetes and heart disease.

Proretinal nanoparticles are a safe and effective way to deliver retinal to the skin.

Thermal imaging is a useful non-invasive method to diagnose active inflammation in frontal fibrosing alopecia.

Primary care is key in managing PCOS, focusing on lifestyle changes and medications like birth control and metformin.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.