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Changing neuroactive steroid levels early in life can affect how adult rats respond to alcohol's stimulating effects.

Centratherum anthelminticum seed extract effectively treats Polycystic Ovary Syndrome in rats.

Eating high-glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

Men and women have different levels and production of brain steroids, which may affect their risk for certain brain disorders.

Hormones during puberty increase certain receptors in the brain, and this change is influenced by estrogen levels.

Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

Testosterone increases fluid secretion and aquaporin expression in the vas deferens, which is important for male fertility.

Blocking neurosteroid production can lead to more seizures and faster epilepsy onset in rats.

Mitochondrial problems in diabetic nerve damage might cause pain by lowering the production of certain nerve-related steroids.

Finasteride reduces alcohol withdrawal effects, especially in female mice.

Changing neuroactive steroids in baby male rats affects their memory and learning differently as they grow up.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Allopregnanolone increases KCC2 expression in baby male rats' brains, while finasteride doesn't affect it.

Women with moderate body hair have higher levels of certain hormones and may benefit from treatment that increases sex hormone-binding protein.

The letter suggests testosterone replacement therapy might worsen COVID-19 outcomes.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

Certain gene variations are linked to higher male hormone levels in Chinese women with PCOS and insulin resistance.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

Finasteride given to baby rats reduces dopamine release and increases alcohol consumption in adult males.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Androgens slow hair growth by altering Wnt signaling in balding cells.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

Human hair follicles can make and process prostaglandins, which may affect hair growth.