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Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

Low testosterone can cause a heart rhythm problem in men, but fixing it can prevent the issue.

Eccrine sweat gland's clear cells likely cause excessive sweating in hyperhidrosis.

Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.

Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Megestrol acetate helps fat-derived stem cells grow, move, and turn into fat cells through a specific receptor.

The study created a new method to test drugs that affect hormone processing in skin.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

COVID-19 may harm male reproductive health and lower testosterone levels, potentially affecting fertility and causing erectile dysfunction. More research is needed.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

c-kit affects hair growth and color in alopecia areata and androgenetic alopecia.

Early anti-aging hair treatments should focus on anti-inflammatory agents and promoting healthy hair growth cycles.

Higher GPER-1 levels are linked to more severe and shorter-duration androgenetic alopecia, suggesting GPER-1 as a potential treatment target.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

Low testosterone in men is a risk factor for a specific heart rhythm issue, and testosterone treatment may help prevent it.

Estrogen helps prevent artery plaque by stopping monocyte capture in blood vessels.

New genes and pathways are important for testosterone production and male sexual development.

Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

COVID-19 may harm male fertility and damage the reproductive system.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Female pattern hair loss involves hormonal factors, genetics, and may be linked to low ferritin levels.

Custom software found that common allergy drugs might have new uses for various conditions and could improve survival in some cancers.

Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.