research Hair Follicle Targeting with Nanoparticles
Nanoparticles can be used to deliver drugs to hair follicles, potentially improving treatments for conditions like acne and alopecia, and could also be used for vaccine delivery and gene therapy.
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research The Role of Dexamethasone in Mediating the Contradictory Effects of Wnt Antagonists SFRP2 and SFRP3 on Human Hair Follicle Growth
Dexamethasone affects hair growth by altering levels of proteins that either promote or inhibit hair follicle growth.
research Mechanism of Action of Avicennia Marina Heartwood Extract and Avicequinone C on Human Dermal Papilla Cells Isolated from Androgenic Alopecia Patients
Avicennia Marina extract and avicequinone C can reduce hair loss hormone production and increase hair growth factors, suggesting they could be used to treat androgenic alopecia.
research Hair Changes Caused by Aging
Aging causes hair to gray and thin, with the timing of graying varying by race, and factors like oxidative stress and genetics can lead to hair loss.
research Drugs That Affect Autonomic Functions or the Extrapyramidal System
Some drugs can cause serious side effects like heart issues and nervous system problems, but certain drugs for Parkinson's and overactive bladder may be safer, though they still have some common side effects.
research Blue Light in Dermatology
Blue light can help treat skin conditions like eczema and acne without major side effects.
research Wanted, Dead and Alive: Why a Multidisciplinary Approach Is Needed to Unlock Hair Treatment Potential
Different fields of expertise must work together to better understand hair growth and create effective hair loss treatments.
research New Effects of Caffeine on Corticotropin-Releasing Hormone (CRH)-Induced Stress Along the Intrafollicular Classical Hypothalamic-Pituitary-Adrenal (HPA) Axis (CRH-R1/2, IP3-R, ACTH, MC-R2) and the Neurogenic Non-HPA Axis (Substance P, p75NTR and TrkA) in Ex Vivo Human Male Androgenetic Scalp Hair Follicles
Caffeine may help reduce stress-induced hair loss.
research Comparison of the Acute Ultraviolet Photoresponse in Congenic Albino Hairless C57BL/6J Mice Relative to Outbred SKH1 Hairless Mice
B6.Cg-Tyr c−2J Hr hr /J mice have a stronger delayed sunburn reaction and are good for UV research.
research Optimization and Transfollicular Delivery of Finasteride-Loaded Proniosomes for Hair Growth Stimulation in C57BL/6Mlac Mice
Finasteride-loaded proniosomes effectively promote hair growth in mice.
research Minoxidil Delivered Via a Stem Cell Membrane Delivery Controlled Release System Promotes Hair Growth in C57BL/6J Mice
A new method using stem cell membranes to deliver Minoxidil improved hair growth in mice better than Minoxidil alone.
research Cell Death by Cornification
Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.
research Understanding, Recognizing, and Managing Toxicities of Targeted Anticancer Therapies
Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.
research Proliferative and Non-Proliferative Lesions of the Rat and Mouse Integument
The project created a standardized system for classifying skin lesions in lab rats and mice.
research Biological Activities of 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-Glucoside in Antiaging and Antiaging-Related Disease Treatments
THSG from a Chinese plant helps with aging and related diseases.
research Cutaneous Gene Therapy
Cutaneous gene therapy could become a viable treatment for skin and hair disorders with improved vector development and gene expression control.
research Exosomes Based Advancements for Application in Medical Aesthetics
Exosomes show promise for improving wound healing, reducing aging signs, preventing hair loss, and lightening skin but require more research and better production methods.
research Multidimensional Profiling of Human Body Hairs Using Qualitative and Semi-Quantitative Approaches with SR-XRF, ATR-FTIR, DSC, and SEM-EDX
Body hairs can be used in forensic science and toxicology like scalp hair.
research South Asian Epidemic of Antifungal Therapeutic Failures: Congress Proceedings and Take-home Messages. First International Congress of SAARCUM: South Asian Alliance Against Recalcitrant Cutaneous Mycosis. 17 November 2018, Medanta – The Medicity, Gurugram, India
The congress concluded that misuse of antifungal drugs in South Asia has led to widespread treatment failure, and new approaches and regional cooperation are needed.
research Status of Research on the Development and Regeneration of Hair Follicles
New regenerative medicine-based therapies for hair loss look promising but need more clinical validation.
research Melampus and the Cure of Proetus' Daughters
Melampus might have cured Proetus' daughters, who possibly had ergotism or Cushing's syndrome, using the herb Helleborus niger, but a mix of factors could have caused their symptoms.
research Proceedings of the Ninth World Congress for Hair Research 2015
The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.
research Melatonin as a Major Skin Protectant: From Free Radical Scavenging to DNA Damage Repair
Melatonin protects the skin by scavenging free radicals and repairing DNA damage.
research The Role of Melatonin in Neuroectodermal-Mesodermal Interactions: The Hair Follicle Synthesizes Melatonin and Expresses Functional Melatonin Receptors
Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.
research Melatonin Increases Anagen Hair Rate in Women With Androgenetic Alopecia or Diffuse Alopecia: Results of a Pilot Randomized Controlled Trial
Melatonin helps hair growth in women with hair loss.
research Mechanism of Sleep Disturbance in Children with Atopic Dermatitis and the Role of the Circadian Rhythm and Melatonin
Children with atopic dermatitis often have sleep problems due to itching and may benefit from melatonin, which helps with sleep and skin symptoms.
research Murine Skin as a Target for Melatonin Bioregulation
Melatonin affects mouse skin and may regulate skin functions.
research Growth of Secondary Hair Follicles of the Cashmere Goat In Vitro and Their Response to Prolactin and Melatonin
Prolactin and melatonin can stimulate hair growth in Cashmere goat hair follicles, but melatonin may reduce follicle viability over time.
research Adrenal Steroid Hormone Concentrations in Dogs with Hair Cycle Arrest (Alopecia X) Before and During Treatment with Melatonin and Mitotane
Melatonin and mitotane treatment led to hair re-growth in 62% of dogs with Alopecia X, but this was not always linked to normal hormone levels.
research Effect of Constant-Release Melatonin Implants and Prolonged Exposure to a Long Day Photoperiod on Prolactin Secretion and Hair Growth in Mouflon (Ovis Gmelini Musimon)
Melatonin implants and long daylight hours alter the timing of hormone release and hair growth in mouflon sheep.