5 citations
,
August 1925 in “Archives of dermatology” This article presents a case of an 8-year-old boy with Recklinghausen's disease showing features such as café-au-lait spots, alopecia, and developmental anomalies, but reports no new findings beyond observation.
161 citations
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June 1994 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that the switch-off of melanogenesis during the hair cycle in C57 BL-6 mice is a gradual and stochastic process starting in mid anagen VI, with specific biochemical markers indicating the transition to catagen.
9 citations
,
March 1996 in “Pediatric dermatology” People of African or Asian descent have unique skin issues that need special care.
17 citations
,
April 2004 in “Acta Clinica Belgica” This study found that ultraviolet light-enhanced visualization can detect subtle skin changes linked to carotene and vitamin A deficiency, which improved with dietary correction in deficient individuals.
1 citations
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July 2025 in “Frontiers in Genetics” In this study, researchers classified melanomas by filaggrin expression levels and found that in filaggrinHigh melanomas, there are significant changes in FGFR signaling and impaired GNA14 and Th1 signatures, linked to genetic and immune alterations associated with pruritus.
4 citations
,
March 2024 in “Journal of Investigative Dermatology” SPRY1 deficiency in skin cells causes stem cells to move to the skin surface, leading to increased pigmentation.
35 citations
,
October 2019 in “Journal of pediatric health care” This article reviews the clinical presentations, pathophysiology, and treatment options for various skin conditions in children with skin of color and reports no new findings.
72 citations
,
November 1997 in “Clinics in dermatology” This review discusses the potential autoimmune etiology of vitiligo and its association with other autoimmune diseases but provides no new research findings; the authors highlight various treatment options.
14 citations
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January 2018 in “Skin Appendage Disorders” This case report suggests that identifying hyperpigmentation on the upper eyelid with specific dermoscopy patterns could help diagnose facial lichen planus pigmentosus without needing a facial biopsy.
1 citations
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November 2024 in “Life” In this study, Desmodesmus pannonicus water extract demonstrated significant antioxidative properties, inhibited melanin production, promoted wound healing in human keratinocyte cells, and showed potential for hair growth enhancement in human follicle dermal papilla cells, suggesting its promise for future dermatological applications.
19 citations
,
November 1985 in “Archives of Dermatology” This case study documented a black male newborn developing large bullae that healed with hypopigmentation, suspecting proteolytic enzymes in keratinocytes caused the collagenolysis responsible for the condition.
5 citations
,
February 2022 in “Frontiers in physiology” This review discusses the role of various cells outside the hair follicle in regulating melanocyte stem cells and hair graying, but reports no new clinical results.
July 1974 in “Archives of Dermatology” This case report details the lack of confluent repigmentation in an 8-year-old girl with vitiligo after three years of trioxsalen and ultraviolet light treatment.
July 2022 in “European Journal of Dermatology” In this study, researchers found that patients with psoriasis had a higher probability of achieving and maintaining a clinical response using brodalumab compared to ustekinumab over 52 weeks, as measured by a multistate modelling approach based on absolute PASI scores.
1 citations
,
October 2019 in “International Journal of Dermatology and Venereology” This review discusses the role of zebrafish as a model for studying human hereditary pigmentary disorders and reports no new experimental results, emphasizing their genetic similarities and the genetic tools available.
April 2026 in “Indian Journal of Dermatology” This case report documents an unusual instance of follicular vitiligo in a young woman, characterized by selective hair depigmentation on the forearms, distinctive dermoscopic and Wood's lamp findings, and histological evidence suggesting functional impairment rather than complete loss of follicular melanocytes.
82 citations
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November 1985 in “Archives of Dermatology” This case report describes a black male newborn who developed bullae that healed with hypopigmentation, linked to collagenolysis and RER vacuoles potentially containing proteolytic enzymes.
September 2024 in “Pigment Cell & Melanoma Research” This study found that mitochondrial fusion regulator Opa1 is crucial for maintaining melanocyte stem cells during the hair follicle cycle in mice, with Opa1 deficiency leading to impaired SCF-KIT signaling, reduced melanocyte populations, and early hair graying.
January 2021 in “Journal of clinical and cosmetic dermatology” This review highlights the role of the skin's photosensory system in mediating responses to UVA radiation, contributing both to immediate protective effects and to broader circadian and seasonal adaptations, but reports no new experimental results.
47 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This review examines the pathogenesis of premature hair graying and potential treatment avenues, but reports no new experimental outcomes, highlighting ongoing research challenges and hopes for drug development.
January 1999 in “Journal of the European Academy of Dermatology and Venereology” RAPK is a rare skin disorder with pigmented spots, mainly on hands and feet, starting in youth.
January 2011 in “Journal of The American Academy of Dermatology” Two patients had a rare combination of red skin spots and white scaly skin lesions not on the genitals.
140 citations
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August 2010 in “Pigment Cell & Melanoma Research” This article discusses mouse genetic studies to explore factors influencing melanogenesis, highlighting pH and cysteine's roles, and proposes a hypothesis for human hair color diversity; it reports no new results.
November 2024 in “Journal of Investigative Dermatology”
January 2026 in “Stem Cell Reviews and Reports” Hair graying may help prevent cancer by protecting stem cells.
14 citations
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December 2009 in “Der Hautarzt” 7 citations
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July 2013 in “Acta Biochimica Polonica” In this study, researchers found that cyclophosphamide treatment unexpectedly reduced splenic melanin deposition in a murine model, whereas this effect was down-regulated more by the normal and dystrophic catagen phase of the hair cycle.
March 2026 in “Journal of Skin and Stem Cell” In this study, lower serum adiponectin levels and altered lipid profiles were observed in patients with periorbital melanosis, suggesting an association with metabolic syndrome.
September 2023 in “Curēus” This case study describes a 21-year-old male diagnosed with Becker's nevus, characterized by hyperpigmented and hypertrichotic lesions that developed over several years.
7 citations
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January 2008 in “Indian Journal of Dermatology” This review discusses the clinical manifestations and genetic basis of pigmentary mosaicism, highlighting its varied phenotypic expressions, but reports no new clinical results.