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    Glossary Melanocyte

    cell producing melanin, pigment for skin, hair, eyes

    A melanocyte is a type of cell found in the skin, eyes, and hair follicles that produces melanin, the pigment responsible for the color of your skin, hair, and eyes. These cells play a crucial role in protecting the skin from harmful UV radiation by absorbing and dissipating it. In conditions like vitiligo or certain types of alopecia, the function or presence of melanocytes can be disrupted, leading to changes in pigmentation.

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    1. In Vivo Role of Vitamin D Receptor Signaling in UVB-Induced DNA Damage and Melanocyte Homeostasis 2016 · 10 citations
    2. Mitochondrial deoxyguanosine kinase depletion induced ROS causes melanocyte stem cell exhaustion and hair greying Cell Regeneration · 2025
    3. Stress-sensing in the human greying hair follicle: Ataxia Telangiectasia Mutated (ATM) depletion in hair bulb melanocytes in canities-prone scalp Scientific reports · 2020 · 14 citations
    4. Non-pigmentary actions of alpha-melanocyte-stimulating hormone--lessons from the cutaneous melanocortin system. PubMed · 2006 · 16 citations
    5. Protective Effect of Superoxide Dismutase Against Hair Graying in a Mouse Model¶ Photochemistry and Photobiology · 2004 · 33 citations
    6. Protective Effect of Superoxide Dismutase Against Hair Graying in a Mouse Model<sup>¶</sup> Photochemistry and Photobiology · 2004 · 12 citations
    7. Hair cycle and hair pigmentation: dynamic interactions and changes associated with aging Micron · 2003 · 152 citations
    8. Human Hair Graying Revisited: Principles, Misconceptions, and Key Research Frontiers Journal of Investigative Dermatology · 2023 · 21 citations
    9. Deficiency in Nucleotide Excision Repair Family Gene Activity, Especially ERCC3, Is Associated with Non-Pigmented Hair Fiber Growth PloS one · 2012 · 10 citations
    10. The multiple uses of azelaic acid in dermatology: mechanism of action, preparations, and potential therapeutic applications Postępy Dermatologii i Alergologii · 2023
    11. Development of Heritable Melanoma in Transgenic Mice Journal of Investigative Dermatology · 1998 · 75 citations
    12. 285 A new scalp treatment for anti-ageing hair Journal of Investigative Dermatology · 2017
    13. Dermal papilla cells and melanocytes response to physiological oxygen levels depends on their interactions Cell Proliferation · 2021 · 7 citations
    14. Aging of the hair follicle pigmentation system International journal of trichology · 2009 · 75 citations
    15. In Vitro Culturing and Harvesting of Human Plucked Hair Follicles Journal of Bioresource Management · 2015
    16. ASPCR‐ASDR 2013 Pigment Cell & Melanoma Research · 2013
    17. Melanocytes: The new Black The International Journal of Biochemistry & Cell Biology · 2006 · 93 citations
    18. Acquired immunogenicity of DNA after modification with malondialdehyde in patients with alopecia areata Scandinavian journal of clinical and laboratory investigation · 2014 · 10 citations
    19. Somatic mutations distinguish melanocyte subpopulations in human skin bioRxiv (Cold Spring Harbor Laboratory) · 2026
    20. Skin melanocytes: biology and development Postepy Dermatologii I Alergologii · 2013 · 401 citations
    21. Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration Cell · 2011 · 260 citations
    22. Melanocyte stem cells: a melanocyte reservoir in hair follicles for hair and skin pigmentation Pigment Cell & Melanoma Research · 2011 · 240 citations
    23. Human Epidermal Neural Crest Stem Cells (hEPI-NCSC)—Characterization and Directed Differentiation into Osteocytes and Melanocytes Stem Cell Reviews and Reports · 2011 · 91 citations
    24. Molecular Regulation of Melanocyte Senescence Pigment Cell Research · 2002 · 85 citations
    25. The silver locus product (Silv/gp100/Pmel17) as a new tool for the analysis of melanosome transfer in human melanocyte–keratinocyte co‐culture Experimental dermatology · 2008 · 68 citations
    26. A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease Nature Communications · 2019 · 67 citations
    27. From neural crest cells to melanocytes: cellular plasticity during development and beyond Cellular and Molecular Life Sciences · 2019 · 66 citations
    28. Keratinocytes regulate the function of melanocytes 2014 · 55 citations
    29. Wnt/β-catenin signaling pathway activates melanocyte stem cells in vitro and in vivo Journal of Dermatological Science · 2016 · 45 citations
    30. Transient mitochondrial DNA double strand breaks in mice cause accelerated aging phenotypes in a ROS-dependent but p53/p21-independent manner Cell Death & Differentiation · 2016 · 42 citations