In Vivo Role of Vitamin D Receptor Signaling in UVB-Induced DNA Damage and Melanocyte Homeostasis

    October 2016 in “ ˜The œjournal of investigative dermatology/Journal of investigative dermatology ”
    Sharmeen Chagani, Sergiy Kyryachenko, Y. Yamamoto, Shigeaki Kato, Gitali Ganguli‐Indra, Arup K. Indra
    TLDR Vitamin D receptor helps protect skin cells from UV damage and supports their growth.
    The study investigated the role of Vitamin D receptor (VDR) signaling in UVB-induced DNA damage and melanocyte homeostasis. It concluded that VDR signaling played a protective role against UVB-induced DNA damage in the skin. The research highlighted that VDR was crucial for maintaining melanocyte homeostasis, which is essential for skin pigmentation and protection against UV radiation. The findings suggested that enhancing VDR signaling could be a potential strategy for preventing UVB-induced skin damage and disorders related to melanocyte dysfunction.
    Discuss this study in the Community →

    Cited in this study

    1 / 1 results