TLDR Vitamin D receptor helps protect skin cells from UV damage and supports their growth.
The study investigated the role of Vitamin D receptor (VDR) signaling in UVB-induced DNA damage and melanocyte homeostasis. It concluded that VDR signaling played a protective role against UVB-induced DNA damage in the skin. The research highlighted that VDR was crucial for maintaining melanocyte homeostasis, which is essential for skin pigmentation and protection against UV radiation. The findings suggested that enhancing VDR signaling could be a potential strategy for preventing UVB-induced skin damage and disorders related to melanocyte dysfunction.
148 citations,
October 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Mice without the vitamin D receptor are more prone to UV-induced skin tumors.
120 citations,
February 2009 in “Apoptosis” Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
8 citations,
April 2016 in “Experimental dermatology” B6.Cg-Tyr c−2J Hr hr /J mice have a stronger delayed sunburn reaction and are good for UV research.
1 citations,
September 2013 in “Elsevier eBooks” Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.
139 citations,
February 2014 in “Journal of Advanced Research” Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.
16 citations,
October 2023 in “Molecular cancer” New treatments like nanotechnology show promise in improving skin cancer therapy.
