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    Glossary Melanin Content

    amount of pigment determining skin, hair, and eye color

    Melanin content refers to the amount and type of melanin pigment present in the skin, hair, and eyes. Melanin is produced by cells called melanocytes and is responsible for the coloration of these tissues. Higher melanin content results in darker pigmentation, providing some protection against UV radiation, while lower melanin content results in lighter pigmentation.

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    1. Carvone Decreases Melanin Content by Inhibiting Melanoma Cell Proliferation via the Cyclic Adenosine Monophosphate (cAMP) Pathway Molecules · 2020 · 12 citations
    2. Biocompatible exosomes derived from <i>Pinctada martensii</i> mucus for therapeutic melanin regulation via α-MSH/NF-κB/MITF pathway Regenerative Biomaterials · 2025 · 1 citations
    3. The forensic limits of hair drug testing: a critical assessment of drug intake and hair concentration relationships Science & Justice · 2026
    4. Dose–hair concentration relationship and pigmentation effects in patients on low-dose clozapine Forensic Science Medicine and Pathology · 2007 · 17 citations
    5. THE EFFECTS OF THE SYNTHETIC AND NATURAL HORMONE OF THE ADRENAL CORTEX ON MELANIN DEPOSITION IN ADRENALECTOMIZED BLACK RATS FED DIETS ADEQUATE AND DEFICIENT IN THE FILTRATE FACTORS OF VITAMIN B<sup>1</sup> Endocrinology · 1945 · 27 citations
    6. Influence of Pigmentation on the Codeine Content of Hair Fibers in Guinea Pigs Journal of Forensic Sciences · 1997 · 53 citations
    7. Methods in hair research: how to objectively distinguish between anagen and catagen in human hair follicle organ culture Experimental Dermatology · 2009 · 132 citations
    8. A pilot study for triple combination therapy with a low-fluence 1064 nm Q-switched Nd:YAG laser, hydroquinone cream and oral tranexamic acid for recalcitrant Riehl’s Melanosis Journal of dermatological treatment · 2016 · 36 citations
    9. Interaction between stem cell factor and endothelin-1: effects on melanogenesis in human skin xenografts Laboratory Investigation · 2006 · 27 citations
    10. Hair growth promoting effect of bioactive extract from deer antler velvet-loaded niosomes and microspicules serum International Journal of Pharmaceutics · 2021 · 14 citations
    11. Reflectance spectroscopy for noninvasive evaluation of hair follicle stage Journal of Biomedical Optics · 2014 · 1 citations
    12. Integrated evaluation of umbilical cord mesenchymal stromal cell-derived extracellular vesicles across skin-related cellular and zebrafish models Frontiers in Bioengineering and Biotechnology · 2026
    13. 한약재 복합추출물이 모발 성장 및 멜라닌 생성 촉진에 미치는 영향 대한본초학회지(본초분과학회지) · 2018
    14. Betamethasone actives cultured amelanotic melanocytes derived from outer root sheath of human hair follicle Linchuang pifuke zazhi · 2008
    15. Structural and Molecular Hair Abnormalities in Trichothiodystrophy 2006 · 71 citations
    16. Genomewide analysis of copy number variants in alopecia areata in a Central European cohort reveals association with <i>MCHR2</i> Experimental Dermatology · 2016 · 29 citations
    17. BIOCHEMICAL AND HISTOCHEMICAL STUDIES ON WHITE, BROWN AND BLACK SKIN REGIONS OF THE GUINEA PIG ACTA HISTOCHEMICA ET CYTOCHEMICA · 1973 · 2 citations
    18. Sex Identification of Feather Color in Geese and the Expression of Melanin in Embryonic Dorsal Skin Feather Follicles Animals · 2022 · 14 citations
    19. Electron Microscope Studies of the Human Epidermis The Clear Cell of Masson (Dendritic Cell or Melanocyte) The Journal of Cell Biology · 1958 · 56 citations
    20. Marie Antoinette Syndrome Archives of Dermatology · 2009 · 36 citations
    21. A comparative study of skin transcriptomes and histological observations for black and white hair colors of giant panda Frontiers in medicine · 2022 · 1 citations
    22. Photochemical alterations in human hair. I. Artificial irradiation and investigations of hair proteins 1995 · 27 citations
    23. Glycine Inhibits Melanogenesis in Vitro and Causes Hypopigmentation in Vivo Biological & pharmaceutical bulletin · 2007 · 19 citations
    24. The Peripheral Clock Regulates Human Pigmentation 2014 · 81 citations
    25. Melanogenesis‐promoting effect of <i>Cirsium japonicum</i> flower extract in vitro and ex vivo International Journal of Cosmetic Science · 2021 · 4 citations
    26. Integrative skin phenotypic and transcriptomic analyses reveal candidate genes for coat color and fiber length in four Chinese goat breeds (<i>Capra hircus</i>) Animal Advances · 2026
    27. α-Mangostin, a safe and natural product as a candidate skin-whitening agent Scientific Reports · 2025
    28. Photodegradation of hair of different ethnicity after 1 year of exposure to natural weathering in Arizona International Journal of Cosmetic Science · 2007
    29. Study on skin care and whitening effects of collagen oligopeptides from puffer skin Zhongguo haiyang yaowu · 2015
    30. Tyrosinase Depletion Prevents the Maturation of Melanosomes in the Mouse Hair Follicle PloS one · 2015 · 31 citations