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240-270 / 1000+ resultsresearch A Phase III, Multicenter, Parallel-Design Clinical Trial to Compare the Efficacy and Safety of 5% Minoxidil Foam Versus Vehicle in Women With Female Pattern Hair Loss.
This study found that 5% minoxidil topical foam used once daily for 24 weeks was well tolerated and significantly improved hair regrowth and scalp coverage in women with female pattern hair loss compared to vehicle foam.
research Malassezia Folliculitis versus Truncal Acne Vulgaris (Clinical and Histopathological Study)
This study found that Malassezia folliculitis, common among young adult males, can be distinguished from truncal acne by its clinical features and responds well to antifungal treatment.
research Detection of Meibomian Gland Dysfunction by in vivo Confocal Microscopy Based on Deep Convolutional Neural Network
This study used in vivo confocal microscopy and a ResNet34 deep learning model to classify meibomian gland images with an AUROC greater than 0.95, indicating its potential for automatic diagnosis and screening of meibomian gland dysfunction.
research Nestin is expressed in HMB‐45 negative melanoma cells in dermal parts of nodular melanoma
This study suggests that nestin is an important marker for identifying HMB-45-negative cells in nodular melanomas, particularly in the dermal parts.
research Hair follicle-derived mesenchymal stem cells decrease alopecia areata mouse hair loss and reduce inflammation around the hair follicle
This study reports that hair follicle-derived mesenchymal stem cells significantly reduced hair loss and inflammation in alopecia areata models, suggesting a potential therapeutic approach.
research Promotion of Skin Carcinogenesis by Dimethylarsinic Acid in Keratin (K6)/ODC Transgenic Mice
This study found that dimethylarsinic acid significantly accelerates skin tumor development in hair follicle-targeted K6/ODC transgenic mice.
research MLO‐mediated Ca2+ influx regulates root hair tip growth in Arabidopsis
This study demonstrated that the FER/MLO signaling module regulates calcium dynamics and ROS accumulation in root hair growth, with the constitutively active MLO (faNTA) able to restore normal development and signaling in specific mutant genotypes, highlighting MLO15's role in root hair tip growth regulation.
research N6-methyladenosine (m6A)-circHECA facilitates the differentiation of SHF stem cells into hair follicle lineage through miR-449a-5p/LEF1 mediated Wnt/β-catenin pathway in cashmere goats
This study found that m6A-circHECA enhances the differentiation of stem cells into hair follicle lineages in cashmere goats by sequestering miR-449a-5p, boosting LEF1 gene expression, and activating the Wnt/β-catenin pathway.
research Follicular induction and CK20+ Merkel cells overlying cutaneous focal mucinosis
This study found that 11% of cutaneous focal mucinosis lesions demonstrated follicular induction, which can mimic basal cell carcinoma histologically and complicate diagnosis.
research A rare case of multiple keratoacanthomas treated with oral acitretin and intralesional methotrexate
This case report describes a 25-year-old male with multiple keratoacanthomas that responded to intralesional methotrexate and oral acitretin treatment.
research TOWARDS NOVEL DIAGNOSTIC MARKER BASED ON BREAST ARTERIAL CALCIFICATIONS
This study evaluated a new computer-aided detection system for identifying Breast Arterial Calcification in mammograms, achieving 70% accuracy, but highlighted the need for a larger dataset to explore its relationship with cardiovascular diseases.
research Manganese-Doped Calcium Silicate Nanowire Composite Hydrogels for Melanoma Treatment and Wound Healing
This study explored the use of manganese-doped calcium silicate nanowire-incorporated alginate hydrogels (MCSA hydrogels) for treating melanoma and promoting wound healing, finding that these hydrogels effectively ablate melanoma under near-infrared irradiation and enhance vascular endothelial cell activity for tissue regeneration.
research Differential cutaneous wound healing in thermally injured MRL/MPJ mice
This study found that MRL/MpJ mice heal burn wounds with scar formation, experiencing delayed wound closure and impaired myofibroblast development, which contrasts with quicker contraction in BALB/c mice.
research A multicenter, randomized, placebo-controlled, double-blind clinical trial of a novel formulation of 5% minoxidil topical foam versus placebo in the treatment of androgenetic alopecia in men
This study found that a new 5% minoxidil foam formulation significantly increased hair counts and improved hair loss condition in men with androgenetic alopecia over 16 weeks compared to placebo.
research Senescence-accelerated Mouse (SAM): With Special Reference to Development and Pathobiological Phenotypes
This review details the development and genetic background of senescence-accelerated mouse strains, provides a comprehensive examination of their phenotypes, and highlights their importance for aging research, but reports no new experimental results.
research Macular Alopecia: A Single‐Center Retrospective Cohort Study to Describe an Underrecognized Pattern of Alopecia
This study identified and described a new form of alopecia termed "macular alopecia," predominantly affecting young Hispanic/Latinx females, characterized by small macules on the scalp with a high rate (63%) of spontaneous resolution in about five months.
research An analysis of gene expression data involving examination of signaling pathways activation reveals new insights into the mechanism of action of minoxidil topical foam in men with androgenetic alopecia
This study observed that 5% minoxidil topical foam alters gene expression and signaling pathways in the scalp, providing insights into its mechanism of action in men with androgenetic alopecia.
research 42380 FFA and Personal Care Product Use, An Investigation into Hair Styling and Stratified Gender Analysis of Facial Sunscreen and Moisturizer: A Systematic Review and Meta-Analysis
This meta-analysis found a significant positive association between frontal fibrosing alopecia and both sunscreen and moisturizer use, with the moisturizer association significant only in males.
research Chemical Fingerprint and Quantitative Analysis for the Quality Evaluation of Platycladi cacumen by Ultra-performance Liquid Chromatography Coupled with Hierarchical Cluster Analysis
This study established a rapid and accurate ultra-performance liquid chromatographic method for chemical fingerprinting and analyzing Platycladi cacumen, effectively distinguishing batches based on geographical and climatic conditions.
research Treatment of Del(5q) Myelodysplastic Syndrome with All-Trans-Retinoic Acid and Tocopherol-α.
This study concluded that the combination of all-trans-retinoic acid and tocopherol-α is not recommended for treating del(5q) myelodysplastic syndromes due to low efficacy and high incidence of adverse effects.
research Progressive Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) from a Young Age Due to a Rare Genetic Disorder, Familial Partial Lipodystrophy: A Case Report and Review of the Literature
This case report highlights a female patient with familial partial lipodystrophy who showed significant improvement in liver stiffness after starting leptin replacement therapy.
research Hypotrichosis with juvenile macular dystrophy: a case report with molecular study
This case report describes a novel mutation in the CDH3 gene in an 11-year-old Iranian boy with sparse scalp hair and macular dystrophy, leading to altered P-cadherin synthesis.
research Acyl-CoA binding protein and epidermal barrier function
This review discusses the role of acyl-CoA binding protein (ACBP) in the epidermal barrier, noting that its disruption in mice is linked to skin and fur abnormalities; it reports no new clinical results.
research Cystathionine β‐synthase‐deficient mice thrive on a low‐methionine diet
In this study, a low-methionine diet significantly improved the health and physical traits of cystathionine β-synthase-deficient mice, contrasting with negative effects on mice with partial deficiency.
research 712 Using scanning electron microscopy to elucidate the role of hair shaft malformation in the pathogenesis of Central Centrifugal Cicatricial Alopecia
Hair shaft malformation contributes to Central Centrifugal Cicatricial Alopecia.
research Very-long-chain Acyl-CoA Synthetases
This review discusses the acyl-CoA synthetase very-long-chain (ACSVL) enzyme family, including its biochemical characteristics, tissue expression, and involvement in lipid metabolism, but presents no new experimental results.
research Retinoid Metabolism Is Altered in Human and Mouse Cicatricial Alopecia
This study found that C57BL/6 mice with a diet containing specific levels of vitamin A showed alterations in retinoid metabolism and increased frequency of cicatricial alopecias, suggesting dietary factors may play a role in this condition.
research Improved cutaneous wound healing after intraperitoneal injection of alpha‐melanocyte‐stimulating hormone
This study found that α-MSH administration before skin wounding in adult mice reduced inflammation and scar area, suggesting a potential pathway to more regenerative healing.
research Primary cicatricial alopecia associated with systemic indolent mastocytosis
Systemic mastocytosis may cause a type of hair loss called cicatricial alopecia.