Macular Alopecia: A Single-Center Retrospective Cohort Study to Describe an Underrecognized Pattern of Alopecia

    April 2025 in “ Pediatric Dermatology
    Molly Thapar, Jonathan L. Feng, Liyun Zhang, Amy Pan, Kristen E. Holland, Yvonne E. Chiu
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    Studysummary This study identified and described a new form of alopecia termed "macular alopecia," predominantly affecting young Hispanic/Latinx females, characterized by small macules on the scalp with a high rate (63%) of spontaneous resolution in about five months.
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    This study identifies and describes a previously unrecognized variant of alopecia, termed "macular alopecia," characterized by small macules < 1 cm in diameter. Conducted as a single-center retrospective cohort study, it included 471 patients, with 74 diagnosed with macular alopecia. This variant showed a predominance in females (77%) and Hispanic/Latinx individuals (62%), with a younger median age of onset at 5.9 years. Macular alopecia primarily affected the parietal scalp and demonstrated a higher rate of spontaneous resolution (63%) within a median of 5 months, compared to patchy alopecia areata (AA), which resolved in 20% of cases over a median of 8 months. The study suggests recognizing macular alopecia as a distinct pattern of non-scarring alopecia.
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