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Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

IL-2 treatment causes skin eruptions and other reversible side effects, and may play a role in psoriasis.

No single treatment is consistently effective for alopecia areata, and more research is needed.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

Children with atopic dermatitis often have sleep problems, affecting their growth and behavior.

Children, especially teenagers, can get severe SARS-CoV infection with symptoms similar to adults, but they typically recover well with supportive care.

Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Liposomes could improve how skin care products work but are costly and not very stable.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.

New treatments for Alopecia Areata show promise but need to be more effective and affordable.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

No treatment fully prevents hair loss from chemotherapy yet.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.