research Modulation of Glucocorticoid Action and the Treatment of Type-2 Diabetes
Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.
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research Conditional Activin Receptor Type 1B (Acvr1b) Knockout Mice Reveal Hair Loss Abnormality
Disrupting Acvr1b in mice causes severe hair loss and thicker skin.
research Localization of Plasminogen Activator Inhibitor Type 2 in Hair and Nail: Implications for Terminal Differentiation
PAI-2 helps in the maturation and protection of hair and nail cells.
research Pharmacogenetic Analysis of Human Steroid 5α Reductase Type II: Comparison of Finasteride and Dutasteride
Dutasteride is more efficient than finasteride, but individual results vary.
research Predominant Expression of 5 Alpha-Reductase Type 1 in Pubic Skin from Normal Subjects and Hirsute Patients
The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.
research Piecing Together the Pigment-Type Switching Puzzle
The document concludes that MGRN1 affects mouse fur color by interfering with a receptor's signaling, but its full role in the body is still unknown.
research Comparison of the Effectiveness of Different Snare Types for Collecting and Retaining Hair from Eurasian Lynx (Lynx lynx)
Wire brush snares are best for collecting Eurasian Lynx hair for DNA analysis.
research Genetic Transformation of Keratoacanthoma-Type Cutaneous Squamous Cell Carcinoma Following Intralesional Chemotherapy
Intralesional chemotherapy with 5-fluorouracil and methotrexate may worsen keratoacanthoma-type skin cancer in transplant patients.
research Natural Killer Group 2 Type D (NKG2D) Gene Polymorphism in Systemic Lupus Erythematosus - Suez Canal Region, Egypt
NKG2D gene polymorphism doesn't affect SLE risk but may influence symptoms like rash and hair loss.
research Contraception Progestin Type and Female Pattern Hair Loss
Newer contraceptives with less androgenic progestins may reduce female hair loss.
research The Long-Term Effect of Specific Type II 5alpha-Reductase Inhibition with Finasteride on Bone Mineral Density in Men: Results of a 4-Year Placebo Controlled Trial
research Acquired Acrodermatitis Enteropathica in a 28-Year-Old Male with Type 1 Diabetes
A 28-year-old man with type 1 diabetes had skin and hair issues due to zinc deficiency.
research Dental Cell Type Atlas Reveals Stem and Differentiated Cell Types in Mouse and Human Teeth
The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.
research Safety of Whole-Body Abrogation of the TRF1 Shelterin Protein in Wild-Type and Cancer-Prone Mouse Models
Deleting the Trf1 protein in mice is safe and may help prevent cancer without major side effects.
![Synthesis and In Vitro Study of 17β-[N-Ureylene-N,N′-Disubstituted]-4-Methyl-4-Aza-5α-Androstan-3-Ones as Selective Inhibitors of Type I 5α-Reductase](/images/research/d19df8a7-8de6-4430-8a0d-4ffa1f502985/small/15608.jpg)
research Synthesis and In Vitro Study of 17β-[N-Ureylene-N,N′-Disubstituted]-4-Methyl-4-Aza-5α-Androstan-3-Ones as Selective Inhibitors of Type I 5α-Reductase
New compounds were made that effectively block a specific enzyme related to androgen conditions.
research A Randomized Controlled Study on the Safety and Efficacy of a Combination of 678nm Helmet-Type Low-Level Laser Therapy and Topical Minoxidil 5% in the Treatment of Male Androgenetic Alopecia
Using a laser helmet with Minoxidil works better for male hair loss than Minoxidil alone, with no extra side effects.
research An Open-Label Pilot Study to Evaluate the Efficacy of Tofacitinib in Moderate to Severe Patch-Type Alopecia Areata, Totalis, and Universalis
Tofacitinib may help treat severe hair loss, but more research is needed.
research The Vitamin D Receptor Is a Wnt Effector That Controls Hair Follicle Differentiation and Specifies Tumor Type in Adult Epidermis
Vitamin D receptor helps control hair growth and could be used to treat certain skin tumors.
research Cross-Sectional Study of Trichoscopy Features, Prevalence, Types of Hair Loss and Hair Care Practices at a Lagos Urban Market
Hair loss is common in the studied community, often linked to aging and hair care practices like braids, weaves, and chemical relaxers.
research Selected Psychological Stress and Cognitive Function Parameters in Patients Suffering from COVID-19 Induced Telogen Effluvium
COVID-19 patients with hair loss experienced more cognitive issues and these issues were linked to higher levels of depression, anxiety, and stress.
research Precise Diagnosis and Therapeutic Effect Evaluation by Dermoscopy and Calcium Fluorescent White Staining for Tinea Capitis and Other Hair Fungal Infection
Combining dermoscopy and calcium fluorescent white staining improves diagnosis and treatment of hair fungal infections.
research Four Days of Simulated Shift Work Reduces Insulin Sensitivity in Humans
Working night shifts for four days can lower the body's ability to use insulin, which may increase the risk of type 2 diabetes.
research Molecular Heterogeneity of Quiescent Melanocyte Stem Cells Revealed by Single-Cell RNA-Sequencing
Different types of resting melanocyte stem cells have unique characteristics and vary in their potential to become other cells.
research Reconsidering PCOS Etiology, Diagnosis, Clinical Subgroups, and Subgroup-Specific Treatments
Different types of PCOS need specific diagnosis methods and treatments.
research Molecular Heterogeneity of Quiescent Melanocyte Stem Cells Revealed by Single-Cell RNA-Sequencing
Different types of inactive melanocyte stem cells exist with unique characteristics and potential to develop into other cells.
research Canonical and Dominant Negative Peroxisome Proliferator-Activated Receptor Gamma Isoforms Are Differentially Expressed in Human Skin and Skin Appendages
Different types of PPARγ are found in varying amounts in human skin and its parts, which could affect how skin treatments work.
research Cell of Origin Contributes to Melanoma Diversity
Different types of stem cells in the skin contribute to the variety of melanoma forms.
research Fibroblast Heterogeneity: Implications for Human Disease
Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
research Skin Cell Heterogeneity in Development, Wound Healing, and Cancer
Different types of skin cells play specific roles in development, healing, and cancer.
research Laser Hair Removal: Principles, Techniques, and Advances
Laser hair removal is the most requested cosmetic procedure and has become a scientifically-based treatment suitable for all skin types.