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Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

Blocking enzymes that help the virus enter cells could be a promising way to treat COVID-19.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.

Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.

The study suggests that motor neurons created from stem cells of patients with spinal and bulbar muscular atrophy show signs of the disease, including changes in protein levels and cell functions.

A specific enzyme is crucial for the bean plant's relationship with certain beneficial soil bacteria and fungi.

Phospholipase A2 enzymes play key roles in skin health and disease.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Gene therapy shows promise for treating skin disorders and cancer, but faces technical challenges.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.

Epimedium extract helps increase skin pigmentation and could be a new treatment for conditions with reduced pigmentation.

sPLA2-X is crucial for normal hair growth and follicle health.

New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.

Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.

Autophagy helps activate hair stem cells and hair growth by changing their energy use to glycolysis.

The document suggests a possible connection between rapid weight loss and hair loss, and reports a case of skin condition improvement after stopping acne medication.

New acne treatments show promise as alternatives to traditional therapies.

Lack of cystatin M/E causes thin hair and dry skin.

M2 macrophages help hair regrowth in wounds by making growth factors.

Phospholipase A2 is necessary for the correct placement of PIN proteins in plant roots, affecting root growth.

Skin problems in COVID-19 patients are rare and may be due to the body's complex immune response or blood clotting issues.