1 citations,
January 2010 in “Elsevier eBooks” Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.
1 citations,
November 1953 in “Archives of Dermatology” The document discusses various challenging skin conditions and their treatments.
COVID-19 can lead to different skin symptoms and might trigger autoimmune diseases in genetically susceptible people.
March 2024 in “International journal of molecular sciences” Mitochondrial dysfunction is linked to various skin conditions and could be a target for treatments.
January 2024 in “Frontiers in immunology” Histone modification is key in treating chronic inflammatory skin diseases.
August 2023 in “Rheumatology” Early referral to a pediatric rheumatologist and thorough evaluation are crucial for treating complex overlap syndromes effectively.
July 2023 in “Journal of the European Academy of Dermatology and Venereology” Hair loss can indicate various health issues, including serious diseases, hormonal imbalances, and can significantly affect personal life and mental health.
May 2023 in “Journal of Investigative Dermatology” People with Alopecia Areata are more likely to have certain health issues like ulcerative colitis and type 1 diabetes, but less likely to have others like hypertension and type 2 diabetes.
January 2023 in “Skin appendage disorders” Hair loss is common in autoimmune diseases and can be an early sign of the condition, often requiring prompt treatment to prevent permanent damage.
December 2022 in “Research Square (Research Square)” The study investigates gene expression in hair follicles affected by chronic discoid lupus erythematosus (CDLE) using bioinformatics methods. By analyzing data from 4 healthy and 7 CDLE-affected hair follicles, and validating with 13 healthy and 47 CDLE-affected scalp samples, the researchers identified key genes through differential expression and WGCNA. These genes, associated with type I interferon response and RIG-1 and IL-17 signaling pathways, were significantly upregulated in both hair follicles and skin tissues. The study also suggests the involvement of follicular helper T cells (Tfhs) in the disease process.
September 2022 in “Dermatology and therapy” Contact immunotherapy might help treat various skin conditions, but more research is needed to confirm its safety and effectiveness.
September 2022 in “Journal of the American Academy of Dermatology” This study analyzed alopecia diagnoses and biopsy rates in lupus patients using data from the U.S. National Ambulatory Medical Care Survey (NAMCS) from 2002-2016 and 2018. It found that only 12.42% of lupus patients with hair loss symptoms received a specific alopecia diagnosis, and just 3.68% underwent a biopsy. Additionally, dermatologists diagnosed alopecia more frequently than family medicine and other specialty groups. The findings suggest that alopecia is underdiagnosed and infrequently biopsied in lupus patients, highlighting the need for clinicians to consider more thorough diagnostic practices or referrals when alopecia is suspected.
May 2022 in “Annals of the Rheumatic Diseases” It's unclear if COVID-19 vaccination causes SLE; more research is needed.
May 2022 in “Rossijskij žurnal kožnyh i veneričeskih boleznej” Alopecia areata is complex, often recurring, and needs personalized treatment, especially with other health issues.
January 2022 in “Przegla̧d dermatologiczny” The exact cause of frontal fibrosing alopecia is unknown, but it's not likely due to sunscreen.
July 2021 in “Rossiiskii Zhurnal Kozhnykh i Venericheskikh Boleznei” Low vitamin D levels are linked to more skin problems.
June 2020 in “International journal of biology, pharmacy and allied sciences” Vitiligo is often found with other autoimmune diseases, which is important to know to help patients.
October 2017 in “Journal of Investigative Dermatology” The study found that sweat glands normally suppress immune responses, but this is disrupted in certain skin diseases, possibly contributing to their development.
January 2015 in “Springer eBooks” Chronic kidney disease can cause hair loss, which may be related to zinc deficiency or certain medications, and sometimes hair grows back when the underlying issue is treated.
July 2002 in “Australasian Journal of Dermatology” Maintaining anticoagulation is crucial for patients with antiphospholipid syndrome.
January 1983 in “Journal of The American Academy of Dermatology” The book is a valuable resource for understanding hair and scalp problems but could be updated with more information on certain conditions.
April 2024 in “Current Rheumatology Reviews” Mixed Connective Tissue Disease (MCTD) in children is rare and often presents with overlapping features of multiple rheumatologic disorders. This report discusses an 8-year-old girl with symptoms including fever, hair loss, lower extremities edema, weakness, and oral ulcers, who was diagnosed with MCTD due to a high titer of anti-U1 RNP antibodies. Treatment with immunomodulator drugs led to disease remission. The case highlights the diagnostic challenges of MCTD in pediatric patients and suggests that serum anti-U1 RNP testing can be a valuable diagnostic tool, especially in cases with recurrent muscular weakness, lupus-like symptoms, and edema.
September 2023 in “Medical and Clinical Case Reports” People with Alopecia Areata often have thyroid problems like Hashimoto thyroiditis and hypothyroidism.
August 2023 in “Dermatology and Therapy” Imiquimod can cause rare skin side effects, some irreversible, and long-term follow-up is important for users.
July 2023 in “Journal of Clinical Medicine” The document concludes that understanding hair follicle histology and the hair cycle is crucial for diagnosing alopecia.
February 2023 in “Siriraj Medical Journal” Not all cases with typical signs of Alopecia Areata are actually diagnosed as such.
March 2022 in “Journal of Investigative Dermatology” The "SnapshotDx Quiz: April 2022" from the Journal of Investigative Dermatology focuses on diagnosing Discoid Lupus Erythematosus (DLE) and highlights that DLE manifests as erythematous plaques on the scalp, which can evolve into alopecic patches. Key findings include the role of IFN-1s in driving inflammation in all cutaneous lupus erythematosus (CLE) types, the presence of senescent cells marked by p16 and p21 in CLE lesions, and the upregulation of the Jak/STAT pathway in CLE. The quiz also notes that serologic abnormalities are uncommon in DLE, antimalarial drugs are effective in treating CLE, and the incidence of squamous cell carcinoma in DLE lesions is low (2-3%). The document suggests a link between inflammation and cellular senescence, with higher levels of p16+ and p21+ cells in more inflamed and chronic conditions.
January 2019 in “Elsevier eBooks” Early detection and skin biopsies are crucial for treating skin cancer and diagnosing various skin conditions.
January 2018 in “Elsevier eBooks” The document concludes that alopecia has various forms, each with specific treatments, but no definitive cure for certain types like CCCA has been proven.
March 2017 in “BIRDEM Medical Journal” Sarcoidosis can cause various skin issues, making diagnosis difficult.