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Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.

Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Certain mutations in a hair growth-related gene cause a type of genetic hair loss.

The HR protein helps hair grow by blocking a hair growth inhibitor, aiding in hair follicle regeneration.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

New treatments targeting specific genes show promise for treating keratin disorders.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

A genetic change in the EDAR gene causes the unique hair traits found in East Asians.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

A20 protein is crucial for normal skin and hair development.

The circadian clock influences the behavior and regeneration of stem cells in the body.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Androgens slow hair growth by altering Wnt signaling in balding cells.

Advanced human skin models improve drug development and could replace animal testing.

The gene Foxq1, controlled by Hoxc13, is crucial for hair follicle differentiation.

Androgens increase a growth factor in hair cells by creating reactive oxygen species, and antioxidants might help treat hair loss.

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.

miR-22, a type of microRNA, controls hair growth and its overproduction can cause hair loss, while its absence can speed up hair growth.

Brg1 is crucial for hair growth and skin repair by maintaining stem cells and promoting regeneration.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Chemokine signaling is important for hair development.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.