May 2005 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” In this study, transgenic mice with a truncated latent transforming growth factor-beta-binding protein showed reduced keratinocyte proliferation and alterations in the hair cycle due to mis-localization of transforming growth factor-beta.
8 citations
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October 2020 in “Lasers in Medical Science” This review suggests that low-level light therapy can promote hair growth in patients with androgenetic alopecia, but more research is needed to standardize treatment parameters and assess long-term safety and efficacy.
33 citations
,
January 2021 in “Aesthetic Surgery Journal” This review suggested that low-level light therapy using red/near-infrared light could be a safe and effective treatment for various skin and hair conditions, though more robust trials are needed to solidify its clinical utility.
64 citations
,
October 2020 in “Journal of lasers in medical sciences” This review discusses the benefits and drawbacks of low-level laser therapy for various non-surgical conditions based on existing literature, but reports no new clinical findings and suggests further research is needed.
15 citations
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May 2017 in “Lasers in Medical Science” This study found that low-level laser treatment may promote hair regrowth in mice by activating the Wnt10b/ß-catenin pathway and inducing the anagen phase of hair follicles.
March 2024 in “Cytologia” In this study, researchers observed that melatonin-mediated LncRNA MTC in Liaoning cashmere goat skin fibroblasts enhances cell proliferation by interacting with the GSTM1 protein, affecting its complex formation with ASK1 and thereby inhibiting apoptosis, which may be relevant for improving cashmere growth.
April 2019 in “Journal of Investigative Dermatology” This review examines clinical trials on low-level laser therapy for pattern hair loss but reports no definitive conclusions, highlighting the need for more controlled studies to resolve uncertainties.
45 citations
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January 2014 in “International Journal of Trichology” This study found that low-level laser therapy may improve hair growth in patients with androgenetic alopecia, either as a standalone treatment or combined with minoxidil or finasteride, without reported adverse reactions.
January 2009 in “Elsevier eBooks” Low level laser therapy may help with hair loss.
July 2017 in “OPAL (Open@LaTrobe) (La Trobe University)” In this study, researchers investigated the role of the ATX-LPA axis in asthma pathogenesis using human and mouse models and highlighted the potential for developing new ATX inhibitors as effective asthma treatments.
January 2018 in “Clinical approaches and procedures in cosmetic dermatology” This review discusses clinical studies on low-level laser therapy for various types of hair loss and suggests it may be promising for those unresponsive to conventional treatments, but reports no new clinical results.
December 2018 in “Zenodo (CERN European Organization for Nuclear Research)” This review of low-level laser therapy for patterned hair loss found that red-spectrum light may be effective for hair growth, but larger case-controlled studies are needed to further support this conclusion.
July 2022 in “Journal of Investigative Dermatology” This study analyzed randomized trials on low-level light therapy combined with minoxidil for androgenetic alopecia, reporting either superior or equivalent hair regrowth compared to minoxidil alone, with initial improvements tapering over time.
10 citations
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March 2015 in “Journal of dermatology” This case report describes a 12-year-old boy with severe skin scaling due to novel compound heterozygous null truncation mutations in the TGM1 gene, resulting in loss of transglutaminase 1 activity.
46 citations
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September 2010 in “Southern Medical Journal” This review discusses low-level light therapy for androgenetic alopecia and female pattern hair loss, noting minimal clinical evidence on its efficacy and the need for more controlled studies.
January 2013 in “프로그램북(구 초록집)” This study found that the Hair660™ low-level light therapy device significantly improved hair density and was safe for men with androgenetic alopecia over 24 weeks.
January 2026 in “Dermatologic Therapy” In this prospective study, individuals with androgenetic alopecia using a home-use low-level laser therapy helmet for 48 weeks experienced significant increases in hair density and thickness, with reported improvements consistent across sexes and no device-related adverse events.
1 citations
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August 2016 in “Pan Stanford Publishing Pte. Ltd. eBooks” This chapter reviews low-level light therapy for hair growth and loss prevention but reports no new clinical results, providing an overview of mechanisms, treatments, and future perspectives.
16 citations
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July 2021 in “American Journal of Medical Genetics Part A” This study identified novel LSS mutations implicated in hypotrichosis simplex with or without neurodevelopmental abnormalities, highlighting the need for careful evaluation of synonymous mutations' potential pathogenic effects.
6 citations
,
September 2018 in “Journal of Dermatological Treatment” This review examines the FDA's 510(k) approval process for low-level laser therapy devices used in treating androgenetic alopecia and reports no new clinical findings.
2 citations
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March 2021 in “Dermatologic Therapy” This study found that low-level laser therapy significantly increased hair counts in women with female pattern hair loss but not in those with telogen effluvium, without serious adverse events.
December 2024 in “Surgery and Clinical Practice” This study suggests that Low-level Laser Therapy may improve pain and quality of life in women with Chronic Pelvic Pain Syndrome, though larger studies are needed to confirm these findings.
1 citations
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January 2021 in “Journal of Cutaneous and Aesthetic Surgery” This review indicates that low-level laser therapy may stimulate hair growth in both men and women with androgenetic alopecia, showing similar efficacy to minoxidil in some studies, but requires more robust evidence.
47 citations
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April 2016 in “Lasers in Surgery and Medicine” This review found that low-level laser therapy appears promising in improving hair regrowth and patient satisfaction in androgenetic alopecia, though results should be interpreted cautiously.
11 citations
,
January 2020 in “Skin appendage disorders” This study reviewed clinical trials and found that low-level laser therapy significantly increased hair diameter or density in both men and women with pattern hair loss compared to a sham device, though the involvement of industry relationships in some studies suggests cautious interpretation.
2 citations
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June 2024 in “Skin Research and Technology” This study found that low-level laser stimulation activates the Wnt signaling pathway, promoting hair follicle stem cell regeneration and accelerating wound healing.
90 citations
,
January 2009 in “Journal of cosmetic and laser therapy” In this study, low-level laser therapy showed no statistically significant improvements in hair growth measures, despite some patients experiencing increases in terminal hairs and shaft diameter.
14 citations
,
January 2020 in “Korean Journal of Family Medicine” This case study reported a rare occurrence of lepromatous leprosy with Lucio phenomenon in a 50-year-old Indonesian living in Malaysia, highlighting the necessity for primary care practitioners, even in non-endemic areas, to recognize this serious leprosy reaction to prevent complications and transmission.
24 citations
,
January 2019 in “Theranostics” This study found that loss of the Pten gene in Lgr5+ hair follicle stem cells promoted squamous cell carcinoma formation through the Akt/β-catenin signaling pathway.
8 citations
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September 2021 in “Facial plastic surgery & aesthetic medicine” This systematic review found that low-level light/laser therapy showed a positive effect in treating male and female pattern hair loss without side effects, as reported by all analyzed randomized controlled trials.