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The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Testosterone's muscle-building effects do not require its conversion to DHT.

Dexamethasone speeds up hair loss in mice, while cyclosporin A slows it down.

Flutamide rarely causes liver toxicity in prostate cancer patients.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

Minoxidil and finasteride are effective for male hair loss, minoxidil for female hair loss, and various treatments like corticosteroids work for alopecia areata; treatment should be tailored to the individual.

Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.

Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.

Finasteride use may lead to less alcohol consumption in men with lasting sexual side effects.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

Medroxyprogesterone injections caused hair regrowth in some dogs with alopecia X.

Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.

TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.

Long COVID causes various long-term health issues and needs better awareness and treatment.

A protein called EGFR protects hair follicle stem cells, and when it's disrupted, hair follicles can be damaged, but blocking certain pathways can restore hair growth.

Hair cortisol may be a good indicator of recent mood in people with bipolar disorder.

Patients with Discoid Lupus Erythematosus have lower vitamin D and antioxidant levels and higher oxidative stress.

The document lists various dermatology topics, treatments, and diagnostic methods.

Castration is preferred for non-breeding male dogs with BPH, but other treatments are available with specific pros and cons.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Clobetasol propionate ointment can help some people with total hair loss regrow hair.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.