1 citations
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April 1987 in “American Journal of Nursing” Some drugs can cause serious side effects, like hypoglycemia from mix-ups, skin reactions, or depression, and while penicillamine may help rheumatoid arthritis more than auranofin, it has more severe side effects.
July 1999 in “Journal of the American Academy of Dermatology” This review discusses valproic acid as a common antiseizure medication associated with alopecia and highlights the need for its inclusion in relevant medical guides, without presenting new clinical findings.
111 citations
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February 1991 in “Headache The Journal of Head and Face Pain” In this study, two-thirds of patients with persistent chronic daily headache significantly improved with divalproex sodium treatment, while liver functions remained unaffected.
April 2026 in “Therapeutic Advances in Drug Safety” This study developed a new clustering model to improve detection of drug-induced cognitive disorder risk signals, finding that it identified drugs with moderate risk signals, like Carbidopa/Levodopa, missed by traditional methods, enhancing clinical assessment comprehensiveness.
May 2022 in “Indian Journal of Pharmacology” This case report highlights a rare instance of valproate-induced hypertensive urgency in a 2-year-old girl, with improvement after stopping the medication.
July 2015 in “Reactions weekly” Lamotrigine can cause hair loss in some patients.
8 citations
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July 2003 in “Journal of the American Geriatrics Society” This case study documents a potential relationship between venlafaxine use and the onset of paranoia, which resolved upon discontinuation and recurred when reintroduced.
September 2021 in “Journal of skin and stem cell” Lactium, a milk protein, can help reduce symptoms of skin disorders linked to stress and anxiety without side effects.
29 citations
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March 1987 in “Therapeutic Drug Monitoring” This study found that venous blood ammonia levels, particularly in patients taking valproate combined with other antiepileptic drugs, were significantly elevated compared to those on valproate alone.
3 citations
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July 2012 in “Indian Journal of Psychological Medicine” Olanzapine helped a man who thought he had bugs on his skin.
November 2001 in “The Journal of neuropsychiatry and clinical neurosciences/The journal of neuropsychiatry and clinical neurosciences” This case report from the University of Alabama describes a rare paradoxical effect where divalproex sodium was associated with increased agitation and hostility in a patient with schizoaffective disorder.
January 2025 in “Seizure” This study found that dual ASM therapies involving valproic acid were associated with poorer tolerability and specific adverse events, with cognitive side effects occurring prominently across all examined combinations.
January 2008 in “Elsevier eBooks” This case study reports that a combination of levetiracetam, zonisamide, and lamotrigine effectively eliminated seizures in a patient with juvenile myoclonic epilepsy, after initial treatments failed.
August 2018 in “Online journal of neurology and brain disorders” This study reported that sodium valproate completely stopped epilepsy in 43% of patients and reduced seizures by 50% in 22% of patients who were resistant to other anticonvulsants.
12 citations
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May 2005 in “Journal of the American Geriatrics Society” This case report describes successful treatment of valproate-induced hyperammonemia in a 79-year-old man using lactulose, marking the first such documented use for this condition.
2 citations
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January 2002 in “Dermatology + psychosomatics” This case study reports that a 15-year-old girl with epilepsy experienced reversible hair loss linked to topiramate adjunctive therapy.
This abstract does not provide any research results; it outlines website navigation and access instructions for the JAMA network.
4 citations
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November 2001 in “Journal of Neuropsychiatry” This case report from the University of Alabama, Birmingham describes a rare paradoxical reaction of increased agitation and hyperactivity in a patient with schizoaffective disorder treated with divalproex sodium.
4 citations
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January 2019 in “PubMed” This study found that low dose valproate monotherapy in epileptic children commonly leads to side-effects like weight gain and decreased appetite, especially among younger patients.
6 citations
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December 1996 in “The Journal of Clinical Pharmacology” Terazosin and finasteride together cause no major issues.
18 citations
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April 2011 in “Neuropharmacology” This study found that metyrapone and etomidate provide dose-dependent anticonvulsant effects against seizures, with delayed effectiveness linked to increased neurosteroid levels.
2 citations
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February 2020 in “Rivista Urologia” Both terazosin and baclofen effectively reduce pain in young men with chronic testicular pain, with no difference in their effectiveness.
1 citations
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May 1992 in “Pharmacological Research” 2 citations
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June 1986 in “Journal of Clinical Pharmacy and Therapeutics” This study demonstrated that certain metal salts can bind to sodium valproate and discussed the potential link to hair loss in patients treated for epilepsy.
18 citations
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January 2009 in “Acta neurologica Scandinavica” In this study, the side effects of long-term sodium valproate treatment for refractory epilepsy were generally slight and transient, with severe side effects not observed.
October 2014 in “Reactions Weekly” 9 citations
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September 2010 in “Dermatologic therapy” This study found that combined therapy with cetirizine and topical steroids stabilized inflammation in most patients with lichen planus pilaris, though one patient experienced cardiac arrhythmia.
60 citations
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December 2013 in “PLoS ONE” The researchers found that inhibiting soluble epoxide hydrolase, either genetically or pharmacologically, delayed the onset of chemically induced seizures related to GABA antagonism in experimental models.
8 citations
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June 2016 in “Journal of Pharmacy Practice” This case report suggests that lisinopril may cause alopecia, which resolved after the patient switched to losartan potassium.
January 2004 in “Headache” This study found that two-thirds of patients with persistent chronic daily headache showed significant improvement with divalproex sodium treatment, although common side effects included weight gain, tremor, hair loss, and nausea.