Treatment of Delusional Infestation with Olanzapine

The document reports a case of a 62-year-old male with a history of delusional infestation, also known as Ekbom's syndrome, where the patient believed he had insects crawling over his body. Despite no evidence of actual insects, the patient experienced significant distress and had consulted various professionals for help. He was also bald due to androgenetic alopecia and had type 2 diabetes, which was well-controlled. The patient was diagnosed with primary delusional infestation and treated with the atypical antipsychotic olanzapine, starting at 2.5 mg and increasing to 10 mg per day. He showed improvement by the fourteenth day and was in full remission at the time of the report, maintained on a 5 mg/day dose of olanzapine. The case suggests that olanzapine can be an effective treatment for delusional infestation and highlights the need for better coordination between dermatologists and mental health professionals in managing such patients.