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Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.

Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.

Oral isotretinoin may slightly improve acne but increases the risk of side effects like dry lips and skin; more research is needed to understand its full risks and benefits.

Insulin resistance might not be enough to worsen blood vessel function in young, nonobese women with polycystic ovary syndrome.

Thallium, mercury, selenium, and colchicine strongly cause hair loss.

Nonantibiotic macrolides show promise for treating various inflammatory skin conditions.

Alkaline Ceramidase 1 prevents early hair loss in mice by keeping hair follicle stem cells balanced.

There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.

Anti-SSB antibodies are useful for diagnosing systemic lupus erythematosus and are linked to specific symptoms.

Mice without certain skin enzymes have faster hair growth and bigger eye glands.

Pegvaliase effectively reduces blood phenylalanine levels in most PKU patients, but requires personalized plans and good communication to manage side effects.

Oxidative stress is higher in women with PCOS, especially if they're obese, and it may increase their risk of heart disease.

Epidermal growth factor helps skin and hair regeneration but needs more research for better understanding.

Forsythiaside A helps reduce brain damage from lack of blood flow by activating certain protective pathways.

Collagen and TGF-β2 help maintain hair cell shape and youthfulness.

Anti-androgens can help manage some PCOS symptoms better than metformin but are not more effective than placebos or birth control pills for other symptoms.

Oral lichen planus is a chronic disease causing mouth discomfort and sometimes needs immunosuppressive treatment.

ALRV5XR significantly improves hair density in women with hair loss and is well-tolerated.

Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.

A substance from Caulerpa racemosa seaweed may protect against skin damage caused by air pollution by reducing oxidative stress and cell death.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Gastric bypass surgery improved a woman's hormonal disorder without the need for medication.

Zinc is important for skin health, and supplements can help treat various skin and hair disorders, but more research is needed for conditions like psoriasis and vitiligo.

Avoid high-tension styles and use professional treatments to reduce hair damage and health risks.

Athletes usually get enough vitamins and minerals from a healthy diet, and supplements are only needed for those with actual deficiencies.

Some antiseizure medications can cause reversible hair loss, with valproate, lamotrigine, and carbamazepine being the most common.

PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.

ALRV5XR effectively increases hair density in men with androgenetic alopecia without adverse effects.

Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.

3D cell cultures are better for testing hair growth treatments than 2D cultures.