research Development of a Non-Parametric Population Pharmacokinetics Model and Bayesian Estimator for Tacrolimus in Tunisian Renal Transplant Patients
The model and estimator can predict drug exposure in kidney transplant patients well.
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research Self-Assessment of a 13-Year-Old Cat with Severe Alopecia, Erythema, and Pruritus Leading to a Diagnosis of Paraneoplastic Alopecia
The cat's skin condition was linked to cancer and did not improve with treatment, leading to a poor outcome.
research Safety of Biological Therapies for Severe Asthma: An Analysis of Suspected Adverse Reactions Reported in the WHO Pharmacovigilance Database
Biologics for severe asthma have known side effects, but some new risks need more study.
research The Efficacy of Terazosin, Finasteride, or Both in Benign Prostatic Hyperplasia
Terazosin and finasteride effectively treat BPH, but combining them adds no extra benefit.
research Pathogenesis of Cardiovascular Alterations in Dogs Treated with Minoxidil
Using minoxidil on dogs can cause serious cardiovascular damage, including arterial injury and hemorrhagic lesions.
research Age Dependence of the Cardiac Lesions Induced by Minoxidil in Rats
Older rats more affected by minoxidil's cardiotoxic effects than younger rats.
research Injectable Silver Nanoclusters-Based Hydrogel for Wound Healing by Eliminating Bacterial Infection and Promoting Tissue Regeneration
The hydrogel with silver and mangiferin helps heal wounds by killing bacteria and aiding skin and tissue repair.
research Prolonged Incubation Period for Cryptococcus Gattii Infection in Cat, Alaska, USA
Cryptococcus gattii can remain dormant in animals for over 8 years.
research Deslorelin for the Treatment of Hair Cycle Arrest in Intact Male Dogs
Deslorelin may help intact male dogs regrow hair from alopecia X, with a 75% success rate and no side effects.
research Inhalation Therapy for Repairing Damaged Elastin Fibers and Decelerating Elastinolysis in Chronic Obstructive Pulmonary Disease
Inhalation therapy may repair and protect elastin in the lungs of COPD patients.
research Spontaneous Fertility in a Male Patient with Testotoxicosis Despite Suppression of FSH Levels
A man with testotoxicosis was fertile despite low FSH levels, suggesting high testosterone may allow sperm production without FSH.
research Generalized Demodicosis and Malasseziosis in a Pug Mix Dog
The dog's skin condition improved significantly after seven days of treatment.
research In Vivo Study of the Effect of 5% and 10% Nebivolol Cream on Hair Growth in Mice Models
Nebivolol cream may be a promising hair loss treatment by improving blood flow and nourishing hair follicles.
research Hypersensitivity Diseases in Horses: Clinical Signs, Diagnosis, and Treatment
The document concludes that various hypersensitivity diseases in horses can be diagnosed and treated with methods like immunotherapy and medication, and early aggressive treatment is crucial for severe diseases like equine cutaneous pythiosis.
research Effect of the Frequency of Injection on the Clinical Responses of Postmenopausal Women to Testosterone Enanthate with Estradiol Valerate
Injecting 2 ml of TEEV every 4 weeks is better because it has the same benefits but fewer side effects.
research Poster Abstract: Novel Dissolving Microarray Patches for Intradermal Delivery of Finasteride
Researchers developed a new skin patch that delivers more finasteride into the skin, potentially improving treatment for hair loss and prostate issues.
research Developmental Origin of Polycystic Ovary Syndrome: A Hypothesis
The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.
research Prolactin Signaling Influences the Timing Mechanism of the Hair Follicle: Analysis of Hair Growth Cycles in Prolactin Receptor Knockout Mice
Prolactin affects when mice shed and grow hair.
research Effects of Minoxidil on Hemodynamics in Patients with Congestive Heart Failure
Minoxidil improves blood flow in heart failure patients.
research Enzymatic and Non-Enzymatic Sulfation Mechanisms in the Biological Actions of Minoxidil
Minoxidil needs activation to work, and minoxidil sulfate helps with hair growth and blood pressure.
research Acute Cardiomyopathy Induced by the Vasodilating Antihypertensive Agent Minoxidil
Minoxidil can cause heart muscle damage in dogs.
research Endocrine Care of Transpeople Part I: A Review of Cross-Sex Hormonal Treatments, Outcomes, and Adverse Effects in Transmen
Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.
research Disease-Modifying Therapy in Multiple Sclerosis: Strategies for Optimizing Management
A comprehensive approach to educating patients and managing side effects is crucial for improving adherence to multiple sclerosis treatments and patient quality of life.
research Recent Advances in Oxasteroids Chemistry
New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.
research Adipose Mesenchymal Stem Cells Combined with Platelet-Rich Plasma Accelerate Diabetic Wound Healing by Modulating the Notch Pathway
Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.
research Hair Follicle Regeneration in Skin Grafts: Current Concepts and Future Perspectives
Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.
research Clinical Comparison of Extended-Release Divalproex Versus Delayed-Release Divalproex: Pooled Data Analyses From Nine Trials
Extended-release divalproex is better tolerated and more effective for seizures and psychiatric symptoms than delayed-release divalproex, but doesn't reduce hair loss.
research Androgen Receptors Are Only Present in Mesenchyme-Derived Dermal Papilla Cells of Red Deer Neck Follicles When Raised Androgens Induce a Mane in the Breeding Season
Red deer only have androgen receptors in neck hair cells for mane growth during breeding season.
research Graphene Oxide–IPDI–Ag/ZnO@Hydroxypropyl Cellulose Nanocomposite Films for Biological Wound-Dressing Applications
The new nanocomposite films are stronger, protect against UV, speed up wound healing, and are antibacterial without being toxic.
research Clinical Case Seminar: Postmenopausal Androgen Excess - Challenges in Diagnostic Work-Up and Management of Ovarian Thecosis
The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.