research Non-Clinical Safety Evaluation and Risk Assessment of Aleglitazar, a Dual PPAR α/γ Agonist, and Its Major Human Metabolite
Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.
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research Agent: Minoxidil
Minoxidil helps lower severe blood pressure and promotes hair growth but can have serious side effects and must be used continuously.
research Effective Amelioration of Hepatic Inflammation and Insulin Response in High-Fat Diet-Fed Rats via Regulating AKT/mTOR Signaling: Role of Lepidium Sativum Seed Extracts
Lepidium sativum seed extracts helped reduce inflammation and improve insulin response in obese rats on a high-fat diet.
research Retinoids: Best Solutions for Acne
Retinoids are effective for acne but can cause serious side effects.
research Nutrition and Hair Health: The Impact of Nutritional Deficiencies
Certain groups may need vitamin supplements to improve hair health and prevent other health problems.
research Caffeic Acid Attenuates Acrylamide Induced Biochemical, Hematological and Histological Alterations in Rats
Caffeic acid helps protect rats from the harmful effects of acrylamide.
research Oral Retinoids: Present Status
Oral retinoids are effective for various skin conditions but have side effects and should not be used during pregnancy.
research Platycladus Orientalis Leaves: A Systematic Review on Botany, Phytochemistry, and Pharmacology
The leaves of Platycladus orientalis have potential health benefits but require more research for safety and understanding how they work.
research Exploring the Interplay Between Arsenic and Cutaneous Physiology, Pathology, and Regeneration
Arsenic exposure from contaminated water severely damages the skin, causing hair loss, pigmentation changes, irritation, and can lead to skin cancer.
research The Human Tri-Peptide GHK and Tissue Remodeling
The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.
research Advances in Nucleoside Monophosphate Prodrugs as Anti-HCV Agents
New treatments for Hepatitis C show promise but need more research to confirm their safety and effectiveness for clinical use.
research How Should You Use the Lab to Monitor Patients Taking a Mood Stabilizer
Patients on mood stabilizers need regular health checks, but many aren't monitored properly.
research Aldesleukin
Aldesleukin can treat certain cancers and increase HIV patient CD4+ counts but often causes severe side effects.
research Adverse Effects of Opioid Analgesic Drugs
Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.
research Developmental Toxicity of Levo-Alpha-Acetylmethadol (LAAM) in Tolerant Rats
LAAM caused developmental toxicity in tolerant rats without causing birth defects.
research Cardiovascular Toxicity of Minoxidil in the Marmoset
High doses of minoxidil can harm marmoset hearts and kidneys, possibly affecting humans similarly.
research Acute Toxicity Studies and Evaluation of Analgesic Property of Tectona Grandis Methanolic Seed Extract in Swiss Albino Mice
Teak seed extract is safe and reduces pain in mice.
research Liver Cirrhosis and Circadian Rhythm
Taking high doses of fluconazole for a long time can cause reversible hair loss.
research Acute Pancreatitis Following Finasteride Toxicity: A Rare Case Report
Finasteride overdose can cause acute pancreatitis.
research Medical Treatment of Liver Hydatidosis
Surgery is the main treatment for liver hydatidosis, but has risks; albendazole is the most effective drug but can have side effects.
research In Vivo Immunological Toxicity in Mice of Carbon Nanotubes with Impurities
Pure carbon nanotubes are safe for mice, but impure ones cause immune issues and hair loss.
research An Ayurveda Approach to Combat Toxicity of Chemo-Radiotherapy in Cancer Patients
Ayurveda, using herbs like ginger, garlic, and turmeric, can reduce chemo-radiotherapy side effects in cancer patients.
research Assessment of Liver Antioxidant Profile in Plasmodium Berghei Infected Mice Treated with Curative Ethanol Leaf Extract of Musa Paradisiaca
Plantain leaf extract reduces liver oxidative stress in malaria-infected mice.
research Role of S-Palmitoylation by ZDHHC13 in Mitochondrial Function and Metabolism in Liver
ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.
research Weekly Docetaxel in Minimally Pretreated Cancer Patients: A Dose-Escalation Study Focused on Feasibility and Cumulative Toxicity of Long-Term Administration
Giving docetaxel weekly at 40 mg/m² is manageable and has low toxicity for cancer patients.
research The Effect of Active Hexose Correlated Compound in Modulating Cytosine Arabinoside-Induced Hair Loss, and 6-Mercaptopurine- and Methotrexate-Induced Liver Injury in Rodents
AHCC reduces hair loss and liver injury caused by chemotherapy in rodents.
research Role of Ayurvedic Management in Chemical Toxicity of Cosmetics: A Review
Ayurvedic methods can help reduce the harmful effects of chemicals in cosmetics.
research Side Effects of Androgen Deprivation Therapy: Monitoring and Minimizing Toxicity
Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.
research Toxicity Assessment of the Green Dunaliella Salina Microalgae
Dunaliella salina microalgae is safe to eat and may boost health.
research Pegylated Liposomal Doxorubicin: Metamorphosis of an Old Drug into a New Form of Chemotherapy
Doxil is an effective, modified chemotherapy drug with a unique toxicity profile and shows promise in treating certain cancers.