research Update on the Dermatologic Use of Systemic Glucocorticosteroids
Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.
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research Safety of Low-Dose Oral Minoxidil for Hair Loss: A Multicenter Study of 1404 Patients
Low-dose oral minoxidil safely treats hair loss, with hypertrichosis as main side effect.
research Self-Microemulsifying Systems of Finasteride with Enhanced Oral Bioavailability: Multivariate Statistical Evaluation, Characterization, Spray-Drying and In Vivo Studies in Human Volunteers
Improved Finasteride delivery for hair loss treatment.
research Finasteride Versus Cyproterone Acetate-Estrogen Regimens in the Treatment of Hirsutism
Finasteride and CPA-EE2 equally reduce hirsutism, but affect hormone levels differently.
research Ceria Nanozyme-Integrated Microneedles Reshape the Perifollicular Microenvironment for Androgenetic Alopecia Treatment
Microneedles help treat hair loss by improving hair surroundings and promoting growth.
research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research Management of Tinea Capitis in Childhood
To treat tinea capitis in children, oral antifungal medication is necessary, with newer drugs offering shorter treatment times than the traditional griseofulvin.
research Antiandrogen And Hormonal Treatment Of Acne
Certain hormone treatments can improve acne and related conditions in women.
research The Efficacy and Safety of JAK Inhibitors for Alopecia Areata: A Systematic Review and Meta-Analysis of Prospective Studies
Oral JAK inhibitors are effective and safe for treating alopecia areata but may need ongoing use to keep results.
research The Human Gut Chemical Landscape Predicts Microbe-Mediated Biotransformation of Foods and Drugs
The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.
research Genetically-Manipulated Adult Stem Cells as Therapeutic Agents and Gene Delivery Vehicles for Wound Repair and Regeneration
Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.
research Food Deprivation-Induced Expression of Minoxidil Sulfotransferase in the Hypothalamus Uncovered by Microarray Analysis
Food deprivation increases MST enzyme in the brain, possibly affecting energy balance.
research Repurposing Existing Drugs for COVID-19: An Endocrinology Perspective
Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.
research Inhibitory Activities of Puerariae Flos Against Testosterone 5α-Reductase and Its Hair Growth Promotion Activities
Puerariae Flos extract may help treat hair loss by blocking a hair loss-related enzyme and promoting hair growth.
research Safety Concerns Regarding 5α Reductase Inhibitors for the Treatment of Androgenetic Alopecia
5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.
research Microencapsulated Cell Tracking
Microencapsulation helps protect and track therapeutic cells, showing promise for treating various diseases, but more work is needed to improve the technology.
research Clinical and Hormonal Effects of the 5 Alpha-Reductase Inhibitor Finasteride in Idiopathic Hirsutism
Finasteride reduces hair growth and is safe for women with excessive hair.
research Dermatoses of Pregnancy
Pregnancy can cause specific skin conditions that need correct diagnosis and treatment to protect both mother and baby.
research Janus Kinase Inhibition in Down Syndrome: Two Cases of Therapeutic Benefit for Alopecia Areata
JAK inhibitors helped treat hair loss in two people with Down syndrome.
research STAT5 Activation in the Dermal Papilla Is Important for Hair Follicle Growth Phase Induction
STAT5 activation is crucial for starting the hair growth phase.
research Oral Syphilis: Report of Three Cases and Characterization of the Inflammatory Cells
The document concludes that recognizing oral lesions is important for diagnosing syphilis.
research Follow-Up of Adverse Drug Reactions from Peginterferon Alfa-2b—Ribavirin Therapy
Peginterferon alfa-2b and ribavirin therapy for hepatitis C can cause serious side effects, some different from those reported in clinical trials.
research Plasma C19 Steroid Sulfate Levels and Indices of Androgen Bioavailability in Female Pattern Androgenic Alopecia
Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.
research Premature Adrenarche: Early Maturation of Adrenal Glands in Children
Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.
research New Steps Forward in the Neuroactive Steroid Field
Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.
research The Effect of 5-Reductase Inhibitors on Erectile Function
5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.
research Controversies Regarding Transdermal Androgen Therapy in Postmenopausal Women
Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.
research Understanding and Management of Female Pattern Alopecia
The conclusion is that the best approach for treating Female Pattern Hair Loss is a combination of different treatments.
research Endocrinological Evaluation and Hormonal Therapy for Women with Difficult Acne
Hormonal therapy is a good option for women with severe acne, especially when there's a chance of hormone imbalance.
research Androgenetic Alopecia: Treatments and Efficacy
Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.