research Structure of Human Steroid 5α-Reductase 2 with the Anti-Androgen Drug Finasteride
Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
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research Management of the Female With Non-Classical Congenital Adrenal Hyperplasia: A Patient-Oriented Approach
The document concludes that managing non-classical congenital adrenal hyperplasia in females requires personalized treatment, genetic counseling, and a team of specialists.
research Acanthosis Nigricans and the Metabolic Syndrome
Acanthosis nigricans is a skin condition that may indicate a higher risk for insulin resistance and type 2 diabetes, and more research is needed to understand and treat it.
research The Hair Follicle: An Underutilized Source of Cells and Materials for Regenerative Medicine
Hair follicles are valuable for regenerative medicine and wound healing.
research Risk of Erectile Dysfunction Associated with Use of 5-Alpha Reductase Inhibitors for Benign Prostatic Hyperplasia or Alopecia: Population-Based Studies Using the Clinical Practice Research Datalink
Taking 5-α reductase inhibitors for prostate enlargement or hair loss does not significantly raise the risk of erectile dysfunction.
research Acne in Women
Acne is common in women, often hormone-related, negatively affects quality of life, and requires various treatments.
research Polycystic Ovary Syndrome: A Review for Dermatologists
A team approach is crucial for managing PCOS, with dermatologists playing a key role.
research BAF200 Is Required for Heart Morphogenesis and Coronary Artery Development
BAF200 is essential for proper heart and coronary artery formation.
research Understanding and Management of Female Pattern Alopecia
The conclusion is that the best approach for treating Female Pattern Hair Loss is a combination of different treatments.
research Immune Modulation of Hair Follicle Regeneration
Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.
research Genetic Variants Associated with Hyperandrogenemia in PCOS Pathophysiology
Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.
research A Review of Hormone-Based Therapies to Treat Adult Acne Vulgaris in Women
Hormone therapies like birth control pills and spironolactone are safe and effective for treating women's adult acne.
research Role of Stem/Progenitor Cells in Reparative Disorders
Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.
research Finasteride Treatment of Hair Loss in Women
Finasteride may help some women with hair loss, but better options exist.
research Finasteride Induced Gynecomastia: Case Report and Review of the Literature
Finasteride for hair loss may cause gynecomastia; doctors should inform patients.
research Relative Safety and Efficacy of Finasteride for Treatment of Hirsutism
Finasteride reduces hirsutism effectively with fewer side effects but is a second-choice treatment due to safety concerns.
research Relationship Between Serum Concentrations, Hemodynamic Effects, and Cardiovascular Lesions in Dogs Treated with Minoxidil
Higher minoxidil doses in dogs cause faster heart rate, lower blood pressure, and heart issues.
research Recent Advances in the Treatment of Psoriasis
New treatments for psoriasis have improved effectiveness and may reduce long-term side effects when combined with standard therapies.
research Parkinson's Disease and Skin Disorders: Non-Iatrogenic and Iatrogenic Connections
Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.
research Role of Beta-Catenin Activation Levels and Fluctuations in Controlling Cell Fate
Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.
research Systematically Optimized Coenzyme Q10-Loaded Novel Proniosomal Formulation for Treatment of Photo-Induced Aging in Mice: Characterization, Biocompatibility Studies, Biochemical Estimations, and Anti-Aging Evaluation
The new CoQ10 gel protects mouse skin better against aging from UV light than the old gel.
research Long-Term Use of 5α-Reductase Inhibitors and the Risk of Male Breast Cancer
Taking 5α-reductase inhibitors does not significantly increase the risk of breast cancer in men.
research Elevated Serum Androstenedione Is Associated With a More Severe Phenotype in Women With Polycystic Ovary Syndrome
Higher androstenedione levels in women with PCOS are linked to more severe symptoms.
research Ovarian SAHA Syndrome Is Associated With a More Insulin-Resistant Profile and Represents an Independent Risk Factor for Glucose Abnormalities in Women With Polycystic Ovary Syndrome: A Prospective Controlled Study
Ovarian SAHA syndrome makes women with PCOS more resistant to insulin and increases their risk of blood sugar problems.
research Resveratrol Derivatives: A Patent Review (2009–2012)
New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.
research Obesity and Polycystic Ovary Syndrome
Obesity worsens Polycystic Ovary Syndrome symptoms, and weight loss is a key treatment.
research Lupus Panniculitis Clinically Simulating Alopecia Areata
Lupus can look like hair loss from alopecia areata but needs different treatment.
research Inducing Hair Follicle Neogenesis with Secreted Proteins Enriched in Embryonic Skin
Three specific proteins can turn adult skin cells into hair-growing cells, suggesting a new hair loss treatment.
research Skin Manifestations of Insulin Resistance: From a Biochemical Stance to a Clinical Diagnosis and Management
Certain skin conditions can indicate insulin resistance and should prompt lifestyle changes and medical treatment to manage underlying health issues.
research The 5α-Reductase Inhibitor Dutasteride but Not Finasteride Protects Dopamine Neurons in the MPTP Mouse Model of Parkinson’s Disease
Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.