35 citations
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August 1978 in “Australian Veterinary Journal” In this study, a sole diet of Leucaena leucocephala caused hypothyroidism and poor weight gain in steers, but mineral supplementation improved some symptoms without normalizing thyroid hormone levels.
December 2025 in “International Journal of Ayurvedic Medicine” This review reports that Fenugreek seeds contain compounds like Galactomannan and Trigonelline, which show anti-diabetic and anti-hyperlipidemic effects, while Fenugreek leaves have high saponin content, contributing to their anti-microbial activities.
8 citations
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July 1977 in “Lipids” This study found a negative correlation between dietary monoene levels, particularly oleic acid, and the capacity for PGE₂ synthesis in rat skin, with the most severe skin issues noted in those fed Zephyr rapeseed oil.
1 citations
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March 2024 in “International Journal of Pharmaceutical Sciences and Drug Research” In this study on albino mice, Helianthus annuus and Martynia annua seed oil extracts in petroleum ether significantly promoted hair growth in a dosage-dependent manner, with 30 mg/ml showing notable results compared to 2% minoxidil.
1 citations
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May 2014 in “Lipid Technology” This news review reports on the latest developments in lipid technology but presents no new research findings.
This study reports the development of a natural hair conditioner incorporating herbs like flaxseed, turmeric, and fenugreek, demonstrating satisfactory physical characteristics, stability, and potential effectiveness as a cost-effective alternative to commercial chemical hair products.
December 2024 in “Ankara Universitesi Eczacilik Fakultesi Dergisi” This review highlights Nigella sativa L. (black cumin) as a plant with numerous health benefits, noting its rich nutritional profile and reported therapeutic effects such as antioxidant and anti-inflammatory activities, identified through various in vitro, in vivo, and clinical research studies.
January 1997 in “Cosmetics and toiletries” This article introduces a silicone derivative of meadowfoam seed oil and reports its ability to penetrate and repair human hair fibers, suggesting potential use in personal-care products.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this review, researchers highlighted the potential of herbal hair oils made from rosemary (Rosmarinus officinalis) and black sesame (Sesamum indicum) as safe and effective alternatives to synthetic products, citing their antioxidant, anti-inflammatory, and nourishing properties that support scalp health and hair quality.
13 citations
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May 2021 in “Plants” This study found that the n-hexane fraction from Leea indica leaves significantly increased hair growth in mice and showed potential as a natural treatment for alopecia.
14 citations
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July 2017 in “Pakistan Journal of Zoology” Fenugreek leaf extracts significantly promoted hair growth in mice with alopecia.
20 citations
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September 2015 in “Protein expression and purification” This study demonstrated that safflower seeds can be engineered to express oleosin-FGF10, which showed a dose-dependent effect on cellular proliferation, potentially facilitating scalable protein production.
March 2024 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” This study found that substituting soy hulls for corn-based supplements did not significantly affect ewe growth, reproductive performance, or lamb performance in pasture-based hair sheep systems.
In this study, a gel formulation with Fenugreek seed extract demonstrated beneficial effects in reducing hair splitting among patients compared to placebo.
2 citations
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August 2021 in “Journal of pharmaceutical research international” This study concluded that fenugreek seed extract loaded solid lipid nanoparticles demonstrated enhanced skin retention and extended release, suggesting potential as a future alternative treatment for alopecia.
This study found that supercritical fluid extraction of germinated perilla seed significantly promoted hair follicle cell proliferation and gene expression related to hair growth, suggesting its potential as a natural treatment for hair loss.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights the potential of herbal hair oil prepared with rosemary and black sesame for scalp health, hair strength, and appearance, emphasizing their antioxidant and nourishing benefits as a natural alternative to chemical formulations.
December 2019 in “University of Malaya Students Repository” This study found that Soxhlet extraction is more effective at removing the toxin mimosine from Leucaena leucocephala, and mimosine shows promise as a biodiesel additive due to its antioxidative properties.
This review highlights that Fenugreek seeds and leaves contain different bioactive compounds, with seeds showing anti-diabetic and anti-hyperlipidemic effects and leaves exhibiting strong anti-microbial properties. Both parts also provide anti-inflammatory benefits and support hair health, underscoring the potential for optimized therapeutic applications from Trigonella foenum-graecum.
May 2024 in “ShodhKosh Journal of Visual and Performing Arts” This study highlights the numerous health benefits of chia seeds, including their rich nutrient profile, cardiovascular protection, digestive support, and potential cognitive and athletic performance enhancements, making them a versatile and powerful functional food for modern diets.
1 citations
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May 2022 in “Pharmaceutics” This study found that a developed nanostructured lipid carrier formulation of tea seed oil can effectively stimulate hair growth and reduce the oily feeling associated with direct application.
1 citations
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December 2020 This study suggests that linoleic acid from Malva verticillata seed extracts may promote hair growth and combat androgenic alopecia by activating Wnt/β-catenin signaling and stimulating dermal papilla cell proliferation in vitro.
4 citations
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January 2023 in “Medical Journal of Babylon” This clinical trial found that hemp seed oil may be a promising treatment for localized alopecia areata, with notable hair regrowth observed in some patients after eight weeks of use.
In this study, researchers reported that topical nanostructured lipid carriers containing tea seed or lavender oil significantly enhanced hair regrowth in female Wistar albino rats over 30 days compared to placebo, with increased hair length and follicular density observed.
January 2026 in “Digilib Repository Unila (Lampung University)” This study found that topical application of celery essential oil at 2% concentration on rabbits significantly boosted hair growth, achieving similar effectiveness to 2% minoxidil in enhancing both hair length and density.
24 citations
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June 2018 in “PubMed” This study found that liposterolic extracts of Serenoa repens enhanced hair regeneration and repair in DHT-induced hair loss mouse models, suggesting potential effects comparable to finasteride.
September 2022 in “Tropical grasslands-Forrajes tropicales” This study observed that smallholder cattle farmers in West Nusa Tenggara, Indonesia using leucaena as feed managed more cattle and focused more on fattening rather than breeding, but leucaena toxicity led to illnesses such as hair loss and, in a few cases, reproductive issues.
33 citations
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January 1977 in “PubMed” This study found that weanling rats fed diets with oxidized rapeseed oil or lard had increased heart lipid levels, various symptoms of fat toxicity, and organ-specific tissue damage.
April 2025 in “Natural Product Communications” This study found that essential oils from A. sinensis and L. sinense 'chuanxiong' were safe and significantly promoted hair regrowth in mice with dehydrotestosterone-induced androgenetic alopecia, outperforming 3% minoxidil in follicle number and dermal thickness improvements, suggesting potential use in hair loss treatments.
7 citations
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April 2011 in “Aktuelle Dermatologie” This study aimed to examine the effects of a nutritional formula containing fenugreek seed extract and micronutrients on androgenetic alopecia, but it reports no new clinical results.