Comparative Overview of Phytoconstituents and Pharmacological Potential of Trigonella Foenum-Graecum Leaves and Seeds

    December 2025
    Amitesh Chakraborty, Prerona Saha
    TLDR Fenugreek seeds help with diabetes and cholesterol, while leaves fight microbes and dandruff.
    This review highlights the distinct phytoconstituent compositions and pharmacological activities of Trigonella foenum-graecum (Fenugreek) leaves and seeds. Fenugreek seeds are rich in compounds like Galactomannan and Trigonelline, which exhibit anti-diabetic and anti-hyperlipidemic properties by reducing glucose and lipid absorption. In contrast, Fenugreek leaves contain high saponin content, providing potent anti-microbial activities, including anti-dandruff and anti-fungal effects. Both leaves and seeds are safe for topical use, offering anti-inflammatory benefits and strengthening hair follicles to reduce hair fall. The study emphasizes the importance of understanding the phytochemistry and pharmacology of Fenugreek for therapeutic optimization and future pharmaceutical development.
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