Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This case study reported that growth hormone therapy dramatically improved rickets symptoms and growth in three children with vitamin-D dependent rickets type 2 who had not responded to standard treatments.

In this study, ALR was found to enhance both the proliferation and osteogenic differentiation of mouse bone marrow mesenchymal stem cells, potentially through specific signaling pathways.

This study found that hair follicle patterning in development may arise from a combination of epidermal prepattern signals and mesenchymal self-organisation, with fibroblast growth factor and bone morphogenetic protein activities playing key roles.

This article highlights the versatility and potential of alginate and its derivatives in tissue engineering applications, discussing their properties, modification techniques, and various uses in enhancing tissue healing, bone regeneration, and cell growth.

This study found that while PRP or nanofat injections improved scarred tissue texture in secondary cicatricial alopecia, they did not significantly enhance hair restoration outcomes compared to hair transplantation alone.

This article reviews the varied clinical outcomes of using platelet-rich plasma for connective tissue healing, highlighting inconsistencies due to differences in PRP preparations and applications, and reports no new clinical findings.

This study summarizes the role and potential applications of stem cell exosomes in skin and bone healing, highlighting their regenerative capabilities and suggesting innovative delivery methods like nanoliposomes and hydrogels to improve bioavailability and therapeutic outcomes.

This article proposes a novel hypothesis that androgenetic alopecia may be mainly caused by skull bone expansion affecting blood supply to hair follicles rather than differences in individual follicle programming, and calls for more genetic research into skull development.

This case report describes a unique occurrence of alopecia totalis resulting in pigmented hair growth over superficial scalp veins in an adult female using augmented betamethasone dipropionate ointment.

This article reviews current osteoporosis treatments, focusing on the potential of selective androgen receptor modulators and other agents to enhance bone formation, but provides no new clinical data.

This article discusses a unique case of permanent chemotherapy-induced alopecia in a patient receiving chemotherapy for breast cancer, characterized by a distinctive histologic finding and excludes bone marrow transplantation, but reports no new clinical results.

This study found that bolandiol increased lean body mass and bone mineral density in castrate adult male rats, exhibiting tissue selectivity and acting through multiple receptor pathways with less potency compared to other androgens.

This review discusses the pathophysiology, diagnosis, and treatment of congenital adrenal hyperplasia, but reports no new research results.

This study found that extracts of mesenchymal stem cells (MSC-extract) and their protein components (MSC-protein) enhanced the proliferation and migration of periodontal ligament cells and induced significant periodontal tissue regeneration, showing potential as a new cell-free treatment for periodontal disease.

This study suggests that the testosterone analogs 7α-Methyltestosterone and 7α-Ethyltestosterone may offer promising androgenic, progestogenic, and anabolic properties for development as male contraceptives.

Wharton's Jelly stem cell medium may help treat skin issues in Systemic Sclerosis.

This narrative review discusses the role of injectable biomaterials in dental tissue regeneration, highlighting their suitability for treating small, hard-to-access oral defects compared to pre-formed scaffolds, and explores the potential use of nanofibers in dental applications.

In this study, researchers reviewed the progress and challenges in using hydrogels for 3D printing in biomedical applications, highlighting advancements in structural complexity, and identifying ongoing issues like resolution improvement, cell viability, and ethical concerns for clinical use.

This article reviews a case of impressive hair regrowth in a man with androgenetic alopecia using a combination of topical minoxidil and tretinoin, but provides no clinical trial results; the authors call for informed consent before recommending this treatment.

This study demonstrated that topical oleuropein induced hair growth in mice by activating the Wnt10b/β-catenin signaling pathway and increasing expression of several growth-related genes in skin tissue.

This study introduces a new multimodal imaging technology to visualize and quantify cell dynamics in natural skin over long durations, demonstrated in GFP bone marrow-transplanted mice, to study dynamic skin regeneration.

In this study, growing human hair follicles in a defined glycosaminoglycan hydrogel ex vivo promoted cell survival, proliferation, and activation of hair growth-related signaling pathways, suggesting GAG-based hydrogels could modulate the hair follicle growth cycle.

This study found that topical administration of the TGFβ mimetic peptide DPS-1 stimulated hair growth in mice by promoting HDP cell proliferation and enhancing hair follicle morphology.

This study found that testosterone therapy increased bone mineral density in older men with low testosterone, and combining it with finasteride may reduce prostate enlargement associated with testosterone treatment.

This study suggests that mesenchymal stem cell-induced dermal papilla-like tissues can generate new hair follicles in mice, indicating potential for developing hair cell therapy using stem cells.

This study found that STAT5 activation in the dermal papilla acts as a key switch to trigger anagen entry in postdevelopmental hair follicle cycling.

This study found that chitosan and surface-deacetylated chitin nanofibrils promoted hair growth in mice and increased fibroblast growth factor-7 production in human follicle dermal papilla cells.

This review introduces an integrated view of hair follicle behavior, highlighting a Yin Yang model of regulation and suggesting glycans as key elements in hair follicle growth control, without reporting new clinical findings.

This study identified two distinct histological patterns in permanent alopecia following bone marrow transplantation, suggesting links to myeloablative chemotherapy and chronic graft-versus-host disease.

This review highlights new treatment options for hair restoration, including platelet-rich plasma and stem cell therapy, which have shown efficacy in increasing hair count and density for androgenetic alopecia and alopecia areata, but presents no original clinical data.