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Mutations in the enzyme don't significantly change how it binds to its specific substances.

The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

Analog 23 is a promising compound for prostate cancer treatment.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

Finding functions for unknown GPCRs is hard but key for making new drugs.

Mutations in the LSS gene cause a rare type of hereditary hair loss.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

Innovative methods are reducing animal testing and improving biomedical research.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Vitamin D is important for bones, hair, blood pressure, and breast development.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

A protein in plants needs to bind two lipids to help with root hair growth, and this process is similar across different plant species.

The research found how GPCR Class A Rhodopsin receptors are related and suggested possible substances they interact with.

Targeting the Smoothened receptor shows promise for treating certain cancers.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

KATP channels are important for energy balance and are targeted by drugs for diabetes, hypoglycemia, hypertension, and hair loss.

Arteannuin might work against cancer and Alzheimer's by targeting neprilysin.

Osthole inhibits the TRPV3 channel by binding to specific sites, potentially aiding drug development for skin diseases and cancers.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.

A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.

R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.

Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.

Honokiol might help reduce male skin aging by maintaining testosterone levels.

Lymphatic vessels are essential for health and can be targeted to treat various diseases.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.