October 2024 in “Journal of Pakistan Association of Dermatologists” In this cross-sectional study, both follicular lichen planus and discoid lupus erythematosus were identified as common causes of scarring alopecia, affecting young people with a more favorable prognosis for hair regrowth in discoid lupus erythematosus compared to follicular lichen planus.
28 citations
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June 1995 in “The Journal of Dermatology” This study reports that flaky skin mice exhibit skin and nail features that closely resemble human psoriasis vulgaris, suggesting they may serve as a natural model for this condition.
July 2023 in “Indian Journal of Animal Health” This study found that fibroblast growth factor 5 may enhance Cashmere goat hair growth by altering the expression of specific genes related to keratin and keratin-associated proteins.
25 citations
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March 2013 in “British Journal of Dermatology” Woman has discoid lupus, frontal fibrosing, and androgenetic alopecia.
October 2021 in “QJM: An International Journal of Medicine” In this pilot study, treatment with lyophilized platelet derived growth factors showed improvement in women with androgenetic alopecia, suggesting it may be a promising new therapy.
57 citations
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October 2013 in “international journal of endocrinology and metabolism” This review discusses clinical features, differential diagnosis, and treatments for female pattern hair loss, emphasizing the use of 2% topical Minoxidil and exploring alternative off-label therapies.
4 citations
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November 2019 in “Dermatology - Open Journal” This study reports that Lichen planus pigmentosus is present in Moroccan patients but remains challenging to treat, with only some experiencing complete resolution of lesions after therapy.
August 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reports that a patient with rare linear lichen planopilaris experienced complete hair regrowth after 12 weeks of treatment with the antibody ixekizumab, suggesting it as a potential targeted therapy.
September 2022 in “The American Journal of Dermatopathology” This study found that IL-17 expression was significantly higher in perifollicular fibrosis of active Lichen planopilaris lesions, suggesting that targeting IL-17 could impact the disease's progression.
Linalool in personal care products may worsen frontal fibrosing alopecia by damaging hair follicle stem cells and triggering harmful immune responses.
47 citations
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September 2013 in “Aaps Pharmscitech” This study found that liquid crystalline nanoparticles formulated with Cremophor surfactants significantly enhanced skin permeation of finasteride compared to lower surfactant concentrations.
April 2018 in “Journal of Investigative Dermatology” This study identified the osteopontin-derived peptide, FOL-005, as a potential inhibitor of unwanted human hair growth by promoting catagen development without reducing stem cell numbers or showing toxicity.
April 2017 in “Journal of Pakistan Association of Dermatology” This study found that female pattern hair loss significantly impacts quality of life, suggesting that psychological support may enhance treatment adherence.
This study found that FGF5 alternative spliceosomes inhibit dermal papilla cell proliferation and regulate hair follicle growth-related gene expression, impacting hair follicle development in rabbits.
January 2017 in “Clinical approaches and procedures in cosmetic dermatology” This review explores clinical studies on low-level laser therapy (LLLT) for alopecia and suggests it may benefit patients unresponsive to conventional treatments, but larger studies are needed to confirm efficacy.
26 citations
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April 2009 in “Australasian Journal of Dermatology” In this study, a 9-year-old girl with female pattern hair loss showed clinical improvement and hair regrowth after six months of daily oral spironolactone.
8 citations
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November 2018 in “Australasian Journal of Dermatology” This study adds evidence suggesting a genetic component to frontal fibrosing alopecia, with daughters experiencing an earlier onset than their mothers, although the clinical pattern remains similar to non-familial cases.
2 citations
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January 2019 in “Skin appendage disorders” This article reports a case of frontal fibrosing alopecia in its early inflammatory stage that responded positively to intralesional steroid treatment.
May 2026 in “Journal of Drugs in Dermatology” New topical treatments and methods can help manage female pattern hair loss.
95 citations
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July 2015 in “European journal of pharmaceutics and biopharmaceutics” This review discusses the application of lipid nanoparticles for enhancing drug delivery through hair follicles and reports no new clinical results, emphasizing the potential role of sebum-like lipids in this context.
4 citations
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June 2017 in “Annales de dermatologie et de vénéréologie” This prospective study in Morocco reported on 20 cases of frontal fibrosing alopecia, finding that dermoscopy played a key role in diagnosing and managing the condition, which can increasingly affect premenopausal women.
January 2026 in “Case Reports in Dermatological Medicine” This report identified a family of Iranian siblings with diverse clinical forms of Lichen Planus, suggesting potential genetic and environmental involvement in its pathogenesis.
15 citations
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August 2019 in “Dermatologic Therapy” This letter details a case report on platelet-rich plasma treatment for a patient with treatment-resistant frontal fibrosing alopecia, but it does not provide new clinical results.
5 citations
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January 2016 in “Skin appendage disorders” This case report describes frontal fibrosing alopecia in a woman with primary biliary cirrhosis and polymyalgia rheumatica, suggesting a possible autoimmune link to this form of hair loss.
21 citations
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February 2017 in “International Journal of Women's Dermatology” This review discusses the physiology and potential hormonal mechanisms involved in female pattern hair loss, as well as the current hormonal and hormone-modifying treatments available, but reports no new research findings.
92 citations
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May 2004 in “Journal of Investigative Dermatology”
9 citations
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January 2020 in “Postepy Dermatologii I Alergologii” This review discusses the enigmatic nature of frontal fibrosing alopecia and reports no clinical results; the authors stress the need for further research.
September 2024 in “Journal of the American Academy of Dermatology” In this case report, a 53-year-old woman with Little-Graham-Piccardi-Lassueur-Syndrome responded well to a treatment regimen of hydroxychloroquine, methotrexate, and other therapies, effectively halting the progression of this rare dermatosis characterized by alopecia and hyperkeratotic eruptions.
August 2023 in “Clinical, Cosmetic and Investigational Dermatology” In this study, the Hamilton-Norwood subtype of female pattern hair loss was associated with early onset and polycystic ovary syndrome, while the Ludwig pattern was more common overall.
1 citations
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May 2014 in “Hair transplant forum international” This commentary explores the challenges and considerations in treating female pattern hair loss, with no new clinical findings reported.