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This study reports a novel mutation in the TP63 gene associated with T and B cell lymphopenia in an EEC patient, suggesting that EEC diagnosis should include TREC assay and evaluation for immunodeficiency.

This study found that the film-trigger applicator system enhanced drug delivery efficiency and skin penetration of dissolving microneedles compared to traditional patch systems in both lab and animal models.

This study identified mefloquine as a potent inducer of lethal ER stress that effectively eliminated vemurafenib-resistant and sensitive melanoma cells, suggesting its potential for repurposing as a melanoma treatment.

In this study, melatonin-loaded Pickering emulsions stabilized by chitosan-dextran sulphate nanoparticles and enhanced with lecithin showed improved photostability, antioxidant activity, and follicular delivery in androgenic alopecia-affected rats, potentially rivaling commercial minoxidil for hair loss treatment.

This study found that a 532 nm laser at 15 J/cm² enhanced the proliferation and differentiation of tendon-derived stem cells in rats, potentially accelerating tendon healing through the up-regulation of Nr4a1.

This case report highlighted an instance of lichen spinulosus emerging as a new cutaneous sequela in a boy following toxic epidermal necrolysis, responding to treatment with ammonium lactate.

In this preclinical study, researchers developed and evaluated a new non-invasive laser system designed for personalized medical use, showing its potential for chronic disease management and adjunctive fat reduction by offering enhanced treatment precision and adaptability over existing devices.

This study identified a novel G207E STING mutation causing a distinct phenotype involving alopecia, photosensitivity, and thyroid dysfunction, and suggests that common polymorphisms in TMEM173 and IFIH1 may influence disease presentation.

This study optimized a screening assay to identify molecules that inhibit or enhance TRPM5 ion channel activity, which may have implications for treating dysfunctions linked to cardiac arrhythmias and diabetes.

This study demonstrated that the human thymus contains clonogenic thymic epithelial cells capable of self-renewal and maintaining a thymic phenotype in a specific culture system.

This study reports that transgene insertion in homozygous transgenic mice causes irreversible hair loss and impaired immune function, linked to interruption of the hairless locus on Chromosome 14.

This article proposes a broad interpretation of tissue engineering as systematically controlling the body's cells, matrices, and fluids, suggesting many existing therapies may fall under this category.

This case report from Tishreen Hospital describes the rare presentation of lupus erythematosus tumidus and autoimmune thyroid dysfunction as initial manifestations of systemic lupus erythematosus, highlighting the importance of early diagnosis for better outcomes.

Minoxidil topical foam is a better, less irritating treatment for hair loss.

MEBO ointment helps activate and grow skin stem cells for burn healing.

This review reports that low-level laser therapy may effectively prevent and alleviate oral mucositis from chemotherapy, supporting its use as a viable treatment option.

This study found that an automated tumor-infiltrating lymphocyte classification algorithm identified thin melanomas with less immune response, which were associated with higher mortality compared to other cases in the study.

In this study, rat primary thymic epithelial cells demonstrated a clonogenic growth pattern in vitro and were able to integrate into functional thymus or differentiate into skin derivatives, similar to skin multipotent stem cells.

This study reported that mammary stem cells in terminal end buds of the mammary gland primarily contribute to branching morphogenesis through dynamic positional regulation and cellular rearrangement.

This study explored the effects of MOTILIPERM on infertility in a rat model with varicocele and oxidative stress, reporting its potential therapeutic efficacy.

This study found that the LEF-1 binding site acts as an enhancer element for the wool keratin intermediate filament gene promoter in hair follicle cortex, with specificity regulated by additional factors.

In this study, Tithonia diversifolia extract was found to improve certain digestive parameters in crossbred sheep but did not enhance growth performance, as the improvements in digestion did not translate into increased body weight or feed conversion.

This study suggests that chronic treatment with TPA in mouse skin selectively expands a keratinocyte subpopulation hyperinducible for ODC, which may be a key target for neoplastic transformation.

Giving melatonin to sheep before the non-breeding season can improve their chances of reproducing in northwest Mexico.

In this study, oral Tribulus terrestris extract significantly increased MSH expression in mouse hair follicle melanocytes, suggesting enhanced melanocyte activity and migration.

This case report describes a rare occurrence of ectodermal dysplasia features in a 14-year-old with MBTPS1 gene variants, expanding the known spectrum of related disorders.

This article discusses the clinical features of tumid lupus erythematosus and emphasizes its importance as a differential diagnosis for noncicatricial alopecia, highlighting a case similar to alopecia areata without reporting new clinical results.

This study found that human epidermal stem cells can adapt to small temperature variations via mTOR signaling, and that prolonged mTORC1 inhibition supports stem cell maintenance.

This commentary discusses the challenges of matrix effects in LC–MS analysis and introduces the concept of a matrix effect factor using stable isotopically labeled internal standards to improve analysis reliability.

This study identified a primitive coarse wool characteristic in Merino sheep that enhances environmental adaptability and fine wool yield without reducing quality, suggesting that epigenetic mechanisms, particularly involving the imprinted Gtl2-miRNAs locus, regulate this advantageous trait.