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Sox2 controls hair color by affecting pigment production in hair follicles.

PCOS is often caused by hormonal imbalances that can lead to various health issues and may indicate a risk for future metabolic and cardiovascular problems.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Human skin can be reconnected to nerves using stem cells, which may help with skin health and healing.

JAK inhibitors show promise for treating various skin diseases.

Foxn1 is important for fat development, metabolism, and wound healing in skin.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

Cetaceans lost hair due to changes in the Hr and FGF5 genes.

Cutaneous gene therapy could become a viable treatment for skin and hair disorders with improved vector development and gene expression control.

The article suggests renaming Polycystic Ovarian Syndrome (PCOS) to "Hyperandrogenic Persistent Ovulatory Dysfunction Syndrome" (HA-PODS) for accuracy and consistency, but no final decision was made.

Isotretinoin therapy for acne can cause many reversible side effects, mainly mild skin conditions, and patient understanding of these effects can improve treatment adherence.

Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.

Spironolactone improved cognitive performance and early sleep quality but not manic symptoms, appetite, or body weight in bipolar disorder when added to sodium valproate.

Lipedema is a painful fat disorder in women that's hard to treat, often worsens with hormonal changes, and requires symptom-focused therapies.

Hormone replacement therapy may improve hair growth in the frontal hairline of postmenopausal women with hair loss.

Brown Adipose Tissue (BAT) could potentially treat Polycystic Ovary Syndrome (PCOS) by controlling energy balance and lipid homeostasis, but more human research is needed.

Certain ESR1 gene variations may affect hormone levels and fat distribution in women with high male hormone levels.

People with androgenic alopecia (AGA) have a higher chance of getting metabolic syndrome.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.

DGAT1 enzyme helps make diacylglycerols, waxes, and retinyl esters.

Understanding how baby skin heals without scars could help develop treatments for adults to heal wounds without leaving scars.

PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.

SCD1 is crucial for skin health and overall energy balance.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

Metabolic Syndrome is linked to several skin conditions, and stem cell therapy might help treat them.

Stem cells can help other stem cells by producing supportive factors.

Androgens play a key role in causing PCOS (Polycystic Ovary Syndrome).

Overweight women with PCOS are more likely to have excess male hormones.

Hormones affect prostate health and disease, with certain hormone imbalances linked to prostate cancer and benign prostatic hyperplasia.