July 2026 in “Journal of the American Academy of Dermatology” Higher fluence low-level laser therapy effectively promotes hair growth in androgenetic alopecia, with varying effects based on sex.
January 2026 in “Dermatologic Therapy” In this prospective study, individuals with androgenetic alopecia using a home-use low-level laser therapy helmet for 48 weeks experienced significant increases in hair density and thickness, with reported improvements consistent across sexes and no device-related adverse events.
January 2024 in “Photodiagnosis and Photodynamic Therapy” The study found that combining a 655nm low-level laser helmet with 2% minoxidil resulted in better improvement in hair diameter and intermediate hair enlargement at the midscalp among Chinese women with FPHL.
October 2023 in “Biomaterials” This review highlights the potential of nanotechnology for hair follicle regeneration, focusing on strategies such as hair cycle modulation, progenitor cell stimulation, and wound-induced hair neogenesis, while also discussing regulatory challenges that may affect the development of these innovative approaches.
April 2022 in “International Journal of Health Sciences (IJHS)” This study found that combining low-level light therapy with platelet-rich plasma significantly improved hair parameters in men with androgenic alopecia, although most improvements decreased after treatment stopped.
64 citations
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October 2020 in “Journal of lasers in medical sciences” This review discusses the benefits and drawbacks of low-level laser therapy for various non-surgical conditions based on existing literature, but reports no new clinical findings and suggests further research is needed.
30 citations
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January 2019 in “International Journal of Trichology” This study observed that androgenetic alopecia significantly impacts the quality of life in males, with personal relationships being notably affected, based on Dermatology Life Quality Index and hair-specific Skindex-29 assessments.
17 citations
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November 2021 in “Journal of Cosmetic Dermatology” This review discusses treatment options for androgenetic alopecia, highlighting the need for personalized, evidence-based approaches but reports no new clinical results.
2 citations
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December 2024 in “Journal of Photochemistry and Photobiology B Biology” This study suggests that pulsed wave photobiomodulation could be a promising treatment for androgenetic alopecia by enhancing dermal papilla cell function through specific light parameters, particularly frequency.
1 citations
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July 2023 in “Cureus” This article examines advancements in understanding and managing androgenic alopecia (male pattern baldness), discussing genetic and psychological factors, diagnostic methods, classifications, and various treatment options, including traditional and emerging therapies, to aid healthcare professionals in making informed treatment decisions.
1 citations
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October 2022 in “Sci” This review discusses the use of helmet designs in integrative medicine and transcranial photobiomodulation, highlighting new developments and potential future advancements in sensor-controlled therapy helmets, but reports no new clinical results.
1 citations
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January 2022 in “Open Access Macedonian Journal of Medical Sciences” This study observed that PRP treatment resulted in greater improvement in hair thickness and density in alopecia areata patients compared to LLLT, with benefits sustained over 12 weeks.
1 citations
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January 2021 in “Indian Dermatology Online Journal” This expert group provided recommendations for preparing and using platelet-rich plasma in treating androgenetic alopecia, suggesting a manual double-spin method and specific dosing, although further studies on injectable platelet-rich fibrin are needed.
1 citations
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September 2019 Laser and light therapies can help regrow hair but need more research for best results.
1 citations
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July 2017 in “Clinical research in dermatology” This review covers the pathogenesis, diagnosis, and potential new treatments for androgenetic alopecia but reports no new clinical findings, highlighting an ongoing need for effective therapies.
March 2026 in “Journal of the American Academy of Dermatology” This clinical review evaluates current evidence on various adjunctive therapies for androgenetic alopecia, highlighting modest benefits for some interventions but emphasizing significant gaps and the need for rigorous, high-quality research to guide effective management strategies.
January 2026 in “Journal of Aesthetic Nursing” This case report observed marked hair regrowth in a patient with refractory alopecia areata using a combination of platelet-rich plasma, low-level light therapy, and microneedling alongside topical and oral agents.
June 2025 in “Clinical Cosmetic and Investigational Dermatology” This study examined the factors contributing to gray hair, such as genetics and lifestyle, and found that while graying correlates with some health conditions, it is primarily a physiological process rather than a pathological one.
February 2025 in “Lasers in Medical Science” This review discusses low-level laser therapy and fractional laser therapies as alternative treatments for androgenetic alopecia, but reports limited evidence of their efficacy due to small sample sizes and potential study biases.
January 2025 in “Journal of Cutaneous and Aesthetic Surgery” This review indicates that various laser therapies, alone or combined with other treatments, show potential in improving hair density and treating androgenetic alopecia, but outcomes can vary, underscoring the importance of personalized treatment.
August 2024 in “Journal of Photochemistry and Photobiology B Biology” In this study, the combination of low level light therapy with arginine, arterial extract, or biotin tripeptide-1 was associated with improvements in hair density and follicle structure in androgenic alopecia.
July 2024 in “Clinical Cosmetic and Investigational Dermatology” In this review, the authors summarized non-pharmacological therapies that may promote hair growth and regeneration as alternatives to traditional drug treatments and hair transplantation, both of which have notable limitations.
December 2023 in “Trials” In this randomized controlled trial involving breast cancer patients undergoing chemotherapy, this study investigated the efficacy of low-level light therapy for preventing hair loss, measuring outcomes like hair count and patient quality of life, but the abstract does not report specific results.
November 2023 in “International Journal of Medical Sciences” This review examines the mechanisms of hair follicle development and regeneration, discussing current hair loss treatments and emerging therapies like low-level laser therapy and stem cell therapy, which the authors suggest show promise in managing hair loss.
July 2023 in “JAAD International” This study describes androgenetic alopecia as a common non-scarring hair loss condition primarily influenced by genetic factors and androgen sensitivity, notably impacting psychosocial well-being, especially in females and younger males seeking treatment.
April 2023 in “Journal of Cutaneous and Aesthetic Surgery” This review proposes a combination treatment scheme with a rotational approach for managing androgenetic alopecia, drawing on evidence for effectiveness, long-term use convenience, and patient acceptance, but presents no new clinical results.
January 2023 in “Dermatologic Therapy” This study evaluated a novel hand-held low-level light therapy device for treating mild-to-moderate acne, finding it significantly reduced inflammatory lesions and moderate acne severity without severe adverse reactions, while also reducing Cutibacterium acnes viability in vitro.
January 2023 in “Skin appendage disorders” This study's review of existing research found insufficient data to determine the impact of skin type on the effectiveness of low-light laser therapy for hair growth in androgenetic alopecia, with a notable lack of data on darker skin types.
December 2018 in “Zenodo (CERN European Organization for Nuclear Research)” This review of low-level laser therapy for patterned hair loss found that red-spectrum light may be effective for hair growth, but larger case-controlled studies are needed to further support this conclusion.
January 2018 in “Clinical approaches and procedures in cosmetic dermatology” This review discusses clinical studies on low-level laser therapy for various types of hair loss and suggests it may be promising for those unresponsive to conventional treatments, but reports no new clinical results.