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The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.

Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.

Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

The new rodent model successfully mimics non-lean human PCOS symptoms.

The Protein-Sparing Modified Fast is effective for rapid weight loss and maintaining it, but requires medical supervision and can have side effects.

Men prefer less invasive cosmetic procedures and need different treatment approaches than women.

Power-enhancing drugs can cause mood swings, aggression, anxiety, and physical side effects, questioning their overall benefits.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Metabolic syndrome and PCOS are related but separate conditions, with metabolic syndrome increasing the risk of heart disease and diabetes.

Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.

The article concludes that proper injection techniques and patient education can prevent serious skin reactions from multiple sclerosis medications.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

We need better ways to test and understand SARMs to make safer and more effective treatments.

New treatments for PCOS focus on managing symptoms and improving fertility.

Testosterone is crucial for development, growth, and various body functions in mammals.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

New treatments for male hypogonadism are effective and should be personalized.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.