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Mutations in three genes cause Uncombable Hair Syndrome, leading to frizzy hair that can't be combed flat.

Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.

Shift work disrupts the body's natural clock, leading to health problems.

Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.

Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.

The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.

Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Certain hairstyles and less hair oil use in African American girls can lead to scalp conditions like traction alopecia and seborrheic dermatitis.

The current methods for diagnosing polycystic ovary syndrome are too vague and may lead to misdiagnosis and problems in research.

Changes in skin microbes play a role in some skin diseases and could lead to new treatments.

Diabetes causes lasting cell dysfunctions, leading to serious complications even after blood sugar is controlled.

Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.

Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.

The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.

Astragaloside IV may help prevent hair loss by blocking a specific pathway that leads to cell death.

HVDRR is caused by VDR gene mutations, leading to vitamin D resistance, treatable with high calcium doses, but alopecia remains permanent.

A scalp infection was treated successfully, leading to full hair regrowth.

Gene linked to common hair loss found, may lead to new treatments.

Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.

Ringworm around the eyes often gets misdiagnosed, leading to eyelash loss, but antifungal treatment can improve the condition.

Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.

Obesity changes androgen levels in women with PCOS, leading to higher testosterone relative to androstenedione.

Psoriasis on the scalp causes smaller oil glands and thinner hair but doesn't lead to hair loss.

Aging causes changes in the scalp that can affect hair growth and lead to older-looking hair in women.

The study found that a specific signaling pathway helps skin wounds heal faster but may lead to larger scars.

Sodium metabisulfite increases sodium channel activity, leading to higher cell excitability and potential damage.

Follicular Cell Implantation might become a new treatment for hair loss and could lead to advances in organ regeneration.

Eating pacu-manteiga fish can cause Haff disease, leading to severe muscle damage.