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research Ginger-Derived Extracellular Vesicles: A Natural Solution for Alopecia
Ginger extracts may help treat hair loss by reducing inflammation and promoting hair growth.
research Fructus Psoraleae Treating Androgenetic Alopecia Through 5-Alpha Reductase Inhibition and Nrf2-Keap1 Pathway
Fructus Psoraleae may help treat hair loss by inhibiting 5-α reductase and affecting the Nrf2-Keap1 pathway.
research Screening the Chemical Composition and Bioactivity of Cerasus Serrulata Flower Extracts Using Two Extraction Methods
Cerasus serrulata flower extracts have strong antibacterial and antioxidant effects and may help prevent hair loss.
research Sdr16c5 and Sdr16c6 Control a Dormant Pathway at a Bifurcation Point Between Meibogenesis and Sebogenesis
Sdr16c5 and Sdr16c6 genes regulate a key point in lipid production that affects eye and skin gland function.
research Glutathione Distribution by Quantitative MALDI Imaging in Reconstructed Human Skin Upon Activation of GSH Biosynthesis by Nrf2 Pathway Activator
Resveratrol activates the Nrf2 pathway in human skin, significantly increasing the production and distribution of the antioxidant glutathione.
research Pharmacology of Topical Finasteride Formulations in Rats
Topical finasteride accumulates in the skin with minimal absorption into the bloodstream.
research Untargeted Scanning of Hair for Drugs of Abuse by Direct Analysis in Real Time–High-Resolution Mass Spectrometry
A new method can quickly and accurately detect drugs in hair.
research Assessment of Multidimensional Health Care Parameters for Developing a Virtual Human Generative Model: A Cross-Sectional Study in Japan
The study aims to create a model to predict health attributes using diverse health data from Japanese adults.
research Design, Synthesis, and Biological Characterization of Metabolically Stable Selective Androgen Receptor Modulators
Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.
research Steroidogenesis Inhibitors Alter But Do Not Eliminate Androgen Synthesis Mechanisms During Progression to Castration-Resistance in LNCaP Prostate Xenografts
Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.
research Long-Term Differential Changes in Mouse Intestinal Metabolomics After Gamma and Heavy Ion Radiation Exposure
Heavy ion radiation has a more severe and long-lasting effect on mouse intestinal metabolites than gamma radiation.
research Sustained Exosome-Guided Macrophage Polarization Using Hydrolytically Degradable PEG Hydrogels for Cutaneous Wound Healing: Identification of Key Proteins and miRNAs, and Sustained Release Formulation
Hydrogel with M2-derived exosomes improves wound healing by slowly releasing exosomes that help reduce inflammation and promote tissue repair.
research Protein Extraction from Human Anagen Head Hairs 1 Millimeter or Less in Total Length
A new method was developed to extract and analyze proteins from very short human hairs.
research Approach to Androgen Excess in Women: Clinical and Biochemical Insights
The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).
research Reductive Stress Selectively Disrupts Collagen Homeostasis and Modifies Growth Factor-independent Signaling Through the MAPK/Akt Pathway in Human Dermal Fibroblasts
Reductive stress messes up collagen balance and alters cell signaling in human skin cells, which could help treat certain skin diseases.
research Guava Leaf Extract as Bioactive Substances for Anti-Androgen and Antioxidant Activities
Guava leaf extract may help treat hair loss and protect cells by blocking certain genes and fighting damaging molecules.
research A Rapid, Simple, Liquid Chromatographic-Electrospray Ionization, Ion Trap Mass Spectrometry Method for the Determination of Finasteride in Human Plasma and Its Application to Pharmacokinetic Study
research International Evidence-Based Guideline on Assessment and Management of PCOS—A Nordic Perspective
The guideline refines PCOS diagnosis, promotes a healthy lifestyle, reviews treatments, and stresses long-term follow-up.
research Antioxidant Capacity and Protective Effect of Cow Placenta Extract on D-Galactose-Induced Skin Aging in Mice
Cow placenta extract has strong antioxidant effects and can delay skin aging in mice.
research Simultaneous Spectrophotometric Determination of Finasteride and Tadalafil in Recently FDA Approved Entadfi Capsules
The methods accurately measure finasteride and tadalafil in Entadfi™ capsules for quality control.
research Anti-Alopecia Activity of Coumarin Derivatives from Merremia Peltata Leaves and Their Binding to Androgen Receptors: A Molecular Study
Scopolin and scopoletin from Merremia peltata leaves may help treat hair loss and showed promising results in rabbit tests.
research Pregnenolone for the Treatment of L-DOPA-Induced Dyskinesia in Parkinson's Disease
Pregnenolone might help manage movement issues caused by Parkinson's disease treatment without reducing the medicine's effectiveness.
research Vitamin D Status Assessment: Lack of Correlation Between Serum and Hair 25-Hydroxycholecalciferol Levels in Healthy Young Adults
Vitamin D levels in hair don't match those in blood, so hair isn't a reliable indicator of Vitamin D status.
research Exploring Rat Corpus Cavernosum Alterations Induced by Finasteride Treatment and Withdrawal
Finasteride changes hormone levels and certain proteins in rats, but these effects can be reversed after stopping the drug.
research Follicular Delivery of Caffeine from a Shampoo for Hair Retention
The new shampoo effectively delivers caffeine to hair follicles to help keep hair, especially as people age.
research Anti-Alopecia Activity of Alkaloids from Noni Fruit Against Dihydrotestosterone-Induced Male Rabbits and Its Molecular Mechanism: In Vivo and In Silico Studies
Noni fruit extract, specifically the FEA-3 sub-fraction, can increase hair growth and reduce baldness in male rabbits, potentially acting like common hair loss treatments.
research The 39th Manfred Donike Workshop on Doping Analysis
The 39th Manfred Donike Workshop discussed methods for detecting misuse of steroids, gene doping, and the complexity of identifying drug residues in urine, highlighting the ongoing efforts to improve global anti-doping work.
research Ocfentanil Testing in Hair from a Fatality Case: Comparative Analysis of a Lock of Hair Versus a Single Hair Fiber
Both a lock of hair and a single hair strand can show chronic drug use, but at least six single hairs are needed for accurate results.
research Hair Regenerative Activities of Flavonoid-Rich Extract of Equisetum Hyemale in Chemically-Induced Alopecia in Sprague Dawley Rats
The flavonoid-rich extract of Equisetum hyemale can help regrow hair in cases of alopecia.