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A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Riboflavin 5′-phosphate (FMN) shows potential for treating androgen-related conditions but may be limited in treating prostate cancer.

Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

ROXY proteins help plants respond to nitrate shortage by affecting nutrient sensing and growth.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

Intravenous calcium therapy is a safe and effective treatment for a rare type of rickets.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

The vitamin D receptor helps maintain hair and bone health even without binding vitamin D.

Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.

The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Mice with human gene experienced hair loss when treated with DHT.

LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.