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This study suggests that glaucoma patients may face increased risk of optic nerve injury if prescribed medications that can lower blood pressure.

This study found that current use of benzodiazepines, α1-blockers (like tamsulosin, alfuzosin, terazosin), finasteride, and possibly rivastigmine is associated with increased risk of intraoperative floppy iris syndrome in cataract surgery patients.

This review concludes that the global literature supports the efficacy and safety of lipidosterolic extract of Serenoa repens in treating lower urinary tract symptoms, comparable to alpha-blockers and 5α-reductase inhibitors.

In this case study, medical management with trilostane improved clinical signs and normalized serum chemistry in a dog diagnosed with adrenal-dependent hyperadrenocorticism over 80 weeks of treatment.

This report describes a 57-year-old woman with fibrosing alopecia in a pattern distribution, who experienced hair regrowth with combined treatment including hydroxychloroquine and other topical and oral therapies.

This study classified dutasteride, fesoterodine, and finasteride as beneficial for older or frail elderly patients, while suggesting caution or avoidance of α-blockers and antimuscarinics in this group.

This review concludes that global literature supports the lipidosterolic extract of Serenoa repens as efficacious and safe for treating lower urinary tract symptoms, with some studies showing equivalence to common pharmacologic agents.

This study found that supplementing inositol in a diet containing sulfasuxidine prevents symmetrical alopecia and promotes better growth and appearance in rats.

This study highlights that early detection and tailored treatment based on kidney biopsy classification are crucial in managing lupus nephritis to prevent progression to end-stage kidney disease, with a focus on saving nephron cells.

This study found that a substantial number of patients continued tamsulosin and/or finasteride unnecessarily after prostate surgery, with poor documentation and communication contributing to this issue.

This case report describes a rare instance of successful treatment of feline leishmaniosis in a cat, with noted nephrotoxic effects possibly linked to long-term allopurinol use.

Spironolactone can safely lower blood pressure in patients on other blood pressure medications, but may slightly increase the risk of low blood pressure.

In this study, MMF plus prednisolone was found to induce remission in 81% of patients with proliferative lupus nephritis, with fewer adverse effects such as alopecia and amenorrhea compared to CYC plus prednisolone, despite similar overall remission rates.

This study concluded that monthly pulse IV cyclophosphamide is effective for severe lupus nephritis in Indian patients, achieving complete or partial remission in 68.9% of cases, though longer follow-up is needed.

This paper discusses the potential of targeting fibrosis in addressing lower urinary tract symptoms associated with benign prostatic hyperplasia, but it provides no new clinical findings and highlights the need for further research.

In this study, anti-androgenic therapy with finasteride for prostate disease was associated with reduced cardiac hypertrophy in heart failure patients, encouraging further investigation in larger cohorts.

Cromolyn sodium's effectiveness for treating asthma in children under 2 is unclear, possibly more beneficial for older children, and further research is needed.

Jockeys using diuretics without potassium supplements can face health problems.

This study found that high-flux hemodialysis combined with L-carnitine improved heart function, reduced inflammation, and decreased venous fistula complications in maintenance hemodialysis patients.

This article discusses the effectiveness of adrenal cortex compounds E and F in treating connective tissue disorders like rheumatoid arthritis and lupus erythematosus, but it reports no new clinical results.

In this study, the rate of hyperkalemia in women taking spironolactone for acne and related issues was low, but frequent monitoring of potassium trends during treatment may be advisable.

This study suggests that sirolimus and propranolol may reduce abnormal lymphatic endothelial cell proliferation in lymphatic malformations, potentially improving vessel function and patient outcomes.

This study found that activating liver X receptors with an agonist reduced skin fibrosis in experimental models, particularly in inflammation-driven conditions, by inhibiting macrophage infiltration and interleukin-6 release.

In this study, a 9-year-old girl with female pattern hair loss showed clinical improvement and hair regrowth after six months of daily oral spironolactone.

This study examined the incidence of hyperkalemia in women over 65 with female pattern hair loss and spironolactone use, but the findings on risk remain unclear.

This paper reviews the current evidence regarding the off-label use of spironolactone for acne management, noting that despite its long-standing application in acne treatment, it has not yet received FDA approval for this indication.

This study found that stilbamidine and hydroxystilbamidine can inhibit the release of specific enzymes from lysosomes and mitochondria in rabbit liver at certain concentrations, with effects similar to cortisol and chloroquine.

This study found that spironolactone enhanced the effectiveness of non-DNA-damaging cancer drugs gemcitabine and osimertinib in cancer cell lines and a mouse xenograft model, likely by suppressing the anti-apoptotic protein survivin.

This study demonstrated that the IVL-DrugFluidic® platform is effective for mass-producing finasteride-loaded polymeric microspheres for long-acting injectables, maintaining stable drug release without an initial burst for a month.