21 citations
,
December 2022 in “Pharmaceutics” This review found that laser-assisted drug delivery in humans was associated with several adverse effects, but no life-threatening events were reported in the studies examined.
147 citations
,
January 2014 in “American Journal of Clinical Dermatology” This study found that low-level laser treatment with the HairMax Lasercomb significantly increased terminal hair density in both men and women with pattern hair loss, with no serious adverse events reported.
This study examined 144 patients with COVID-19 in Guatemala and found a significant link between skin manifestations, especially those with vasculonecrotic damage, and a higher likelihood of severe to critical illness.
This study found that low-level laser therapy may enhance wound healing and reduce pain, swelling, and inflammation by increasing mitochondrial activity and oxidative stress, leading to greater protein synthesis and cell proliferation.
March 2003 in “International Society of Hair Restoration Surgery” This article reviews the current use of lasers in hair restoration and reports no new findings, summarizing insights from doctors with laser experience.
December 2020 in “Lasers in Surgery and Medicine” In this study, using a 1064 nm picosecond Nd:YAG laser effectively removed undesirable scalp micropigmentation in four patients within 1–3 treatment sessions, with no unexpected adverse events reported.
This article discusses the effects of ablative carbon dioxide laser treatment for skin rejuvenation, noting it requires only a single treatment but involves more complex postoperative management, without reporting new clinical outcomes.
26 citations
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April 1999 in “Dermatologic Clinics” This article reviews the basics of hair follicle biology, laser/tissue interactions, and hirsutism and hypertrichosis causes, discussing the long-pulsed alexandrite laser's role in hair reduction without reporting new clinical results.
6 citations
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November 2018 in “Photodiagnosis and Photodynamic Therapy” This study found that using a wearable low-level light therapy device for photodynamic therapy significantly reduced actinic keratosis lesions and improved quality of life in patients with AK of the scalp.
4 citations
,
January 2011 in “Current problems in dermatology” This article reviews the growing trend of at-home laser and light devices for treating conditions like acne, hair removal, and psoriasis, emphasizing their popularity and the need for cautious use but reports no new clinical results.
2 citations
,
June 2024 in “Skin Research and Technology” This study found that low-level laser stimulation activates the Wnt signaling pathway, promoting hair follicle stem cell regeneration and accelerating wound healing.
February 2022 in “INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH” This study reviewed 44 clinical trials and found that home-based laser devices are effective for short-term hair removal and skin rejuvenation, with common side effects including erythema and edema; additional trials are needed to confirm safety and efficacy.
December 2018 in “Lasers in Surgery and Medicine” This special issue reviews various advances in laser and light-based technologies for dermatological treatments, emphasizing improvements for diverse skin types, but reports no new empirical results.
June 2024 in “Cermin Dunia Kedokteran” This review discusses the benefits and applications of low level laser therapy in cosmetic dermatology, particularly for skin conditions and pigmentation disorders, but reports no new clinical results.
43 citations
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November 2012 in “Pharmaceutical research” This study found that fractional laser treatment significantly enhances the penetration and targeting of certain permeants, such as imiquimod and FD, to skin follicles, but not hydroquinone.
May 2025 in “Drug Delivery and Translational Research” 16 citations
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December 2022 in “Expert Opinion on Drug Delivery” This study reviewed preclinical and clinical research and found that AFL-assisted topical drug delivery is considered safe and effective, enhancing drug efficacy, reducing treatment time and pain, and improving cosmetic and safety outcomes, but larger clinical trials are needed to confirm these benefits.
75 citations
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August 2003 in “International journal of cosmetic surgery and aesthetic dermatology” This study found that low level laser therapy with a HairMax LaserComb improved hair counts and tensile strength in patients with androgenetic alopecia, particularly in males and vertex areas.
September 2021 in “Medical lasers” Laser treatment followed by a special hair growth solution increased hair count and thickness without side effects.
May 2018 in “Journal of Cosmetic and Laser Therapy” The editorial discusses the effectiveness and safety of various laser and energy-based cosmetic treatments.
22 citations
,
September 2022 in “Medicina” This study found that the dual-wavelength non-ablative fractional laser provides enhanced skin rejuvenation by increasing thermal lesion coverage and collagen remodeling compared to using the CO2 laser alone in an ex vivo setting.
51 citations
,
October 2002 in “Archives of dermatology” This case study of a patient with dissecting cellulitis of the scalp found that multiple medications, including isotretinoin, achieved only modest improvement, and symptoms returned after treatments were stopped.
1 citations
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November 2016 in “Experimental and Therapeutic Medicine” In this study using guinea pigs, the low-dose 800 nm semiconductor laser was found to effectively treat skin blackheads and coarse pores by promoting hair follicle cell apoptosis, while maintaining PCNA expression levels in sebaceous glands.
The 1540nm fractional erbium-glass laser helps treat hair loss caused by hormones.
5 citations
,
October 2020 in “Bioengineering & translational medicine” This study demonstrates the use of microscopy-guided laser ablation to create a highly structured 3D hydrogel-based organotypic skin model with folliculoid structures, potentially useful for studying hair follicle development or bioactive substance screening.
160 citations
,
January 2009 in “Clinical Drug Investigation” This study found that the HairMax LaserComb® significantly increased hair density and was safe and well tolerated for treating androgenetic alopecia in men compared to a sham device.
7 citations
,
August 2024 in “Skin Research and Technology” The study's findings are unreliable due to retraction.
1 citations
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January 2019 in “Journal of Nuclear Technologyin Applied Science (JNTAS) (Print)” This study found that low-level laser therapy accelerates skin regeneration in gamma-irradiated mice and enhances the biostimulatory effect on hair follicles.
1 citations
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December 2020 in “Medical lasers” The laser therapy device effectively increased hair growth in people with androgenetic alopecia.
5 citations
,
November 2014 in “Hair transplant forum international” This article introduces a series on low level laser light therapy, focusing on its science, regulatory aspects, and controlled trial methodologies, but reports no new clinical results.