This report presents a rare case of lichen spinulosus in a 52-year-old woman, featuring hyperkeratotic follicular papules and a dense lymphohistiocytic infiltrate in affected skin areas.
24 citations
,
September 1997 in “PubMed” This study concludes that loose anagen hair can develop in adulthood and may be difficult to distinguish from telogen hair loss, with pathologic findings offering limited diagnostic insights.
September 2025 in “British Journal of Dermatology” February 2026 in “JEADV Clinical Practice” This report describes a rare case of scarring alopecia, diagnosed as lichen planopilaris (LPP), affecting solely the limbs, highlighting the necessity for thorough evaluation of LPP beyond the scalp.
February 2023 in “Cosmoderma” An infant with complete hair loss was diagnosed with a genetic disorder affecting hair growth.
23 citations
,
January 2018 in “BMC genomics” This study found that vimentin expression in the hair follicles of Inner Mongolian Cashmere goats is highest during the growth stage and localized to the outer root sheath, suggesting a role in hair cycle regulation.
21 citations
,
April 2000 in “Journal of Cutaneous Pathology” This case report describes a 22-year-old woman with a nevoid plaque termed localized follicular hamartoma, characterized by skin-colored papules and specific cellular and structural features.
August 2021 in “Journal of Investigative Dermatology” This study found that ILC1-like cells can induce alopecia areata in healthy human hair follicles, suggesting that these cells might be a therapeutic target in AA management.
January 2026 in “International Journal of Dermatology Research” This case report discusses a young girl with loose anagen hair syndrome, highlighting the importance of recognizing the condition early to avoid misdiagnosis and unnecessary treatments, and noting her spontaneous improvement with conservative management.
1 citations
,
February 2023 in “All Life” This study identified proteins involved in hair follicle formation in cashmere goat embryos, highlighting potential signaling factors that may drive hair follicle initiation and cashmere growth.
87 citations
,
October 1987 in “Journal of Investigative Dermatology” 7 citations
,
May 2021 in “Clinical Case Reports” This abstract discusses Alopecic and aseptic nodule of the scalp as a rare alopecia condition that may be underdiagnosed and reports doxycycline as a safe and effective treatment option.
75 citations
,
April 2000 in “Developmental Dynamics” This study suggests that the structural integrity and physical proximity of Whn's DNA binding and activation domains are crucial for hair keratin gene activation and may explain the nude phenotype.
17 citations
,
September 2018 in “Matrix Biology” The researchers reported that mouse keratinocyte-specific deletion of laminin γ1 led to delayed coat pigmentation due to impaired melanocyte migration and differentiation, linked to altered laminin composition in the basement membrane.
January 2025 in “Indian Journal of Paediatric Dermatology” This case report documents the youngest recorded instance of a linear variant of alopecia areata in a 4-year-old child, highlighting the uniqueness and rarity of this clinical presentation and noting its possible association with favorable prognosis, though further evidence is needed.
4 citations
,
May 2024 in “Cytotechnology”
4 citations
,
May 2006 in “médecine/sciences” This study suggests that the hairless gene encodes a nuclear factor important for hair follicle integrity, and its absence leads to hair follicle loss and defects in tissue development.
17 citations
,
June 2019 in “BMC genomics” This study cataloged several long non-coding RNAs and microRNAs in cashmere goat dermal papilla cells, suggesting these non-coding RNAs may play a role in hair follicle stem cell activation and hair growth.
16 citations
,
November 2022 in “eLife” This study found that specific genetic changes in both coding and noncoding regions may have independently driven the evolution of hairlessness in various mammalian species through accelerated evolution.
April 2012 in “Development” This study found that Rac1 activity in specific skin compartments is sufficient for hair formation, but results in hair with altered structure and pigmentation compared to normal.
September 2022 in “IP Indian journal of clinical and experimental dermatology” This case report describes an 8-year-old girl with atrichia congenita characterized by complete hair loss and papular lesions, attributed to an insertion mutation in the hairless gene.
40 citations
,
April 2014 in “Genes & Development” The researchers reported that in mice, prolactin signaling in the skin epithelium inhibits hair follicle stem cell activation, promoting quiescence during periods of high serum prolactin like pregnancy and lactation.
8 citations
,
December 2022 in “BMC Genomics” This study revealed gene expression patterns in yak hair follicles during different growth phases, enhancing the understanding of cell fate specialization and providing insights for yak villus development.
January 2024 in “Elsevier eBooks” July 2026 in “Journal of Investigative Dermatology”
November 2022 in “Research Square (Research Square)” This study found that HOXC13 gene expression was significantly higher during the anagen phase in Angora goats, potentially contributing to the mohair's shiny and silky nature.
July 2018 in “Elsevier eBooks” This review discusses primary neutrophilic cicatricial alopecias, their clinical and histological characteristics, and the importance of early therapeutic intervention to prevent scarring alopecia, reporting no new clinical results.
4 citations
,
April 2018 in “The journal of pediatrics/The Journal of pediatrics” This case report discusses a 6-year-old girl with loose anagen hair syndrome, characterized by painlessly shedding hair, and notes no evidence of benefit from biotin supplementation.
January 2006 in “Chinese Journal of Dermatology” In this study, latanoprost at certain concentrations promoted the growth of pig hair follicles in vitro by possibly extending the anagen phase of the hair cycle.
178 citations
,
June 1994 in “Journal of Investigative Dermatology” This study found that a non-scarring alopecia in C3H/HeJ mice resembles human alopecia areata and may serve as a valuable model for studying specific subtypes of the human condition.