2 citations
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August 2020 in “Journal of Nutritional Science and Vitaminology” In this study, yellow Chinese chive extract was observed to protect against acetaminophen-induced liver toxicity in mice by enhancing antioxidant pathways and reducing liver injury markers.
1 citations
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August 2025 in “Frontiers in Bioengineering and Biotechnology” This study found that a 3D wound model, the 3DWoundSE, showed improved responsiveness to injury and cytotoxic stimuli compared to an intact 3D skin equivalent, offering a reproducible and ethical alternative to animal models for early wound response assessment in dermatological research and drug development.
1 citations
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June 2023 in “The FASEB journal” This study found that in mice, LSD1 interacting with HSP90 accelerates skin wound healing by enhancing HFSC glycolytic metabolism, proliferation, and differentiation via the c-MYC/LDHA axis.
1 citations
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January 1996 This study found that cysteine and arginine are crucial for hair growth in hair follicles, with cysteine affecting hair fibre diameter and arginine involved in protein incorporation and energy metabolism.
March 2025 in “International Journal of Molecular Sciences” This study observed that topical application of palmitate or oleate accelerated the onset of the hair growth phase in mice, whereas glycolysis end product lactate delayed it, suggesting metabolic regulation as a promising approach for influencing hair growth.
December 2023 in “Journal of materials chemistry. B” This study found that a nanoemulsion containing perfluorooctyl bromide effectively increased oxygen levels in an anoxic environment, enhancing hair dermal papilla cell growth and significantly promoting hair organ elongation.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers found that while blocking either glycolysis or glutaminolysis in cancer cells did not prevent tumor growth due to metabolic flexibility, simultaneous inhibition of both pathways hindered carcinoma development, indicating multiple interventions may be necessary for effective metabolic manipulation in cancer treatment.
June 2023 in “Research Square (Research Square)” This study found that autophagy activation in hair follicle stem cells shifted their metabolism to glycolysis, which promoted hair growth by initiating the hair follicle cycle.
July 2026 in “Frontiers in Immunology” This review summarizes recent findings on the role of lactylation, a novel post-translational modification, in skin diseases, suggesting its potential as a therapeutic target by linking metabolism, epigenetic regulation, and inflammatory processes.
January 2026 in “British Journal of Dermatology” This study found that neither caffeine nor N,N-dimethylglycine treatments were toxic to balding or nonbalding dermal papilla cells and could stimulate calcium influx, indicating treatment responsiveness.
January 2026 in “Dermatologic Therapy” In this prospective study, researchers identified advanced age, androgenetic alopecia, high levels of lactate dehydrogenase and dihydrotestosterone, and low levels of adenosine triphosphate as independent risk factors for posttransplant telogen effluvium, offering insights for optimizing surgical strategies to reduce PTE risk.
February 2025 in “Iraqi Journal of Science” This study found that women with polycystic ovary syndrome had significantly higher serum lactate dehydrogenase levels and lower levels of cortisol, dopamine, zinc, and vitamin D3 compared to healthy controls.
July 2024 in “Journal of Investigative Dermatology” PP405 may help hair growth by activating hair follicle stem cells.
This study found that activating autophagy in hair follicle stem cells can promote hair growth by shifting their metabolism to glycolysis, while inhibiting it led to delayed hair cycle progression.
In this study, researchers observed that dysregulated innate lymphoid cells type 1, alongside CD8+ T cells, may contribute to the pathogenesis of alopecia areata by affecting hair follicle health.
7 citations
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October 2015 in “American Journal of Primatology” The researchers observed that pregnancy in rhesus monkeys was associated with an increased incidence of hair loss, though the underlying reasons remain unclear.
1 citations
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June 2022 in “Al-Esraa University College journal for medical sciences.” This study found that vitamin D supplementation in vitamin D-deficient patients in Baghdad alleviated symptoms like hair loss, bone pain, and depression, with improvements noted within two months.
1 citations
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December 2013 in “Turkderm” This article discusses the increasing use of plant and plant extracts during pregnancy and lactation, highlighting user perceptions of their benefits and safety but does not present new research findings.
This study found that single-born cashmere goats had higher birth weights, pre-weaning growth rates, and superior cashmere production attributes compared to twin-born goats, despite twin-born goats achieving compensatory growth post-weaning.
February 2026 in “Journal of the American Academy of Dermatology” Managing skin diseases during pregnancy and postpartum requires careful consideration of treatment safety and dosing to protect both mother and baby.
This study used a mouse model to reveal that S100A4-positive cells, specifically fibroblasts and immune cells, play a crucial role in nipple development, essential for successful lactation, despite no issues with mammary morphology or milk production.
March 2024 in “Frontiers in genetics” This study used genomic analysis to reveal moderate genetic diversity, minimal inbreeding, and specific genes under positive selection in Xiangdong black goats, highlighting their unique adaptation traits and potential for breeding and conservation.
May 2022 in “Hormones and behavior” This study found that hair cortisol levels in black-tailed prairie dogs, influenced by factors like predation risk and lactation, were associated with reproductive success, supporting the Cort-Adaptation hypothesis.
This study found that areola formation in mice requires a combination of pregnancy hormones and mechanical strain, with individual stimuli causing only modest changes in epidermal proliferation and connective tissue remodeling.
July 2008 in “Planta Medica” This study found that Acanthus montanus leaves' aqueous extract is a developmental toxicant in rats, leading to several adverse effects on offspring when used during pregnancy.
September 2006 in “Baghdad Science Journal” This study suggests a link between hair loss experienced during pregnancy and lactation and inadequate daily intake of certain nutrients.
August 2006 in “Experimental dermatology” This study suggests that human scalp hair follicles express erythropoietin and its receptor, up-regulating receptor expression under hypoxic conditions, and may mimic another hypothalamus–pituitary axis equivalent involving the TRH-TSH system.
124 citations
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January 1995 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” This article reports a case of Netherton's syndrome that responded to 12% ammonium lactate lotion, suggesting potential treatment benefits for skin and allergic symptoms in this rare condition.
86 citations
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January 1990 in “The Journal of Pediatrics” This study suggests that biotin therapy may be beneficial for individuals with partial biotinidase deficiency, as some developed symptoms later, which resolved with treatment.
15 citations
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March 2019 in “Veterinary Dermatology” This study found that three mousse products containing chlorhexidine and varying antifungal components maintained significant antibacterial activity against S. pseudintermedius in vitro for up to 10 days, while other mousses did not show significant differences.