3 citations
,
September 2021 in “JAAD case reports” This review discusses the increased autoimmune events associated with the use of denosumab, a biologic agent for managing postmenopausal osteoporosis and skeletal complications from malignancy, but reports no new data.
October 2020 in “Journal of Ayurvedic and herbal medicine” In this study, Dheedhi Hair Care herbal shampoo significantly reduced hair fall and dandruff compared to a regular shampoo, with no reported side effects.
8 citations
,
October 2020 in “Pharmaceutics” This study explored using a chitosan oligomer coating for topical delivery of dutasteride-loaded nanostructured lipid carriers, aiming to reduce systemic exposure and cytotoxicity.
3 citations
,
August 2023 in “Drug safety” This source reports that trastuzumab deruxtecan improves outcomes in HER2-positive and HER2-low metastatic breast cancer, emphasizing the need for careful adverse event monitoring, particularly for interstitial lung disease, and managing emetic risk to maximize benefits.
21 citations
,
January 2010 in “JOURNAL OF HEALTH SCIENCE” This study found that abietic acid from pine resin more effectively inhibits testosterone 5α-reductase than several plant extracts, suggesting potential for treating androgen-dependent diseases.
42 citations
,
May 1997 in “The Journal of Biochemistry” In this study, researchers purified and cloned rat peptidylarginine deiminase type III, demonstrating its activity and specific expression in the epidermis and hair follicles.
5 citations
,
December 2021 in “Frontiers in Cell and Developmental Biology” This review outlines how peptidyl arginine deiminases (PADIs) and protein citrullination are involved in hair follicle regeneration and inflammatory alopecia, but presents no new clinical findings.
April 2016 in “Journal of Investigative Dermatology” This study suggests that lithocholic acid may enhance hair regeneration in alopecia by activating vitamin D receptors in human dermal papilla cells.
1 citations
,
June 2019 in “Journal of Biological and Scientific Opinion” This article highlights the health risks associated with adding paraphenylenediamine to mehndi, such as contact dermatitis and asthma, and emphasizes the need for regulatory checks as its use grows among cancer patients, women with alopecia, and pregnant individuals.
January 2023 in “Bioorganičeskaâ himiâ” This study found that a new deoxycholic acid derivative may offer a similar prostatoprotective effect to finasteride with lower toxicity in rat models.
64 citations
,
May 2000 in “International Journal of Dermatology” This study found that thalidomide increased peripheral lymphocyte counts and reduced inflammation in lupus erythematosus patients, but was associated with polyneuropathy, suggesting careful use in refractory cases.
October 2016 in “Letters in Drug Design & Discovery” January 2026 in “Journal of Ethnopharmacology” Cedrol promotes hair growth better than baricitinib by regulating immune cells.
May 2024 in “Journal of molecular structure” This study found that a novel thiohydantoin derivative, 3a, effectively inhibited androgen receptor activity in LNCaP cells and showed promising in vivo results by reducing testosterone-induced prostate changes, outperforming finasteride in mitigating prostate index and histopathological alterations.
62 citations
,
November 2022 in “Acta Pharmaceutica Sinica B” This study reported that an injectable hydrogel based on platelet-rich plasma and laponite improved wound healing in diabetic and normal rats by enhancing angiogenesis and macrophage polarization.
16 citations
,
January 2019 in “Pharmaceutical biology” This study found that Lespedeza cuneata aqueous extract reduced serum dihydrotestosterone levels and 5α-reductase mRNA expression in testosterone-induced prostatic hyperplasia in rats, suggesting potential as a treatment for prostatic hyperplasia.
18 citations
,
January 2002 in “Chemical & pharmaceutical bulletin/Chemical and pharmaceutical bulletin” This study found that several new pregnane derivatives, especially steroids 16 and 19, demonstrated higher antiandrogenic activity on male hamster models than the commonly used finasteride.
January 2026 in “Frontiers in Bioscience-Landmark” This study reported that, in a laboratory setting, araliadiol derived from Centella asiatica activated antioxidant pathways, mitigating urban particulate matter-induced oxidative stress and skin damage.
June 2026 in “Oriental Journal Of Chemistry” This research found that a novel dehydroepiandrosterone derivative (12) significantly reduces cell viability and increases apoptosis in testosterone-stimulated normal and tumor prostate cells, unlike finasteride and dutasteride, which also showed activity under dihydrotestosterone stimulation.
14 citations
,
June 2011 in “Steroids” This study found that several dehydroepiandrosterone ester derivatives effectively reduced prostate and seminal vesicle weight in gonadectomized hamsters treated with testosterone, demonstrating potential antiandrogen effects comparable to Finasteride.
25 citations
,
October 2010 in “Journal of Hepatology” This study presented a case where budesonide was insufficient to maintain remission in autoimmune hepatitis, suggesting it may be less effective than prednisolone and associated with notable steroid side effects.
22 citations
,
June 2002 in “Journal of Medicinal Chemistry” This study found that several synthesized compounds were potent inhibitors of human steroid 5alpha-reductase type 2 and reduced prostate weights in treated rats, with compound 15 showing promise for potency in humans.
July 2026 in “International Journal for Research in Applied Science and Engineering Technology” This study explored the use of Kasisadi Lepa, a classical herbo-mineral formulation, and found its components could reduce dandruff by addressing scalp inflammation, microbial growth, and tissue damage with potential integration into long-term scalp health strategies.
July 1999 in “Journal of the American Academy of Dermatology” This review discusses valproic acid as a common antiseizure medication associated with alopecia and highlights the need for its inclusion in relevant medical guides, without presenting new clinical findings.
129 citations
,
January 2004 in “Journal of medicinal chemistry” This study synthesized nonsteroidal ligands as second-generation androgen receptor agonists and identified three compounds with significant anabolic activity and moderate to minimal androgenic activity in vivo.
2 citations
,
August 2014 in “Journal of dermatological science” This study found that krh/krh rats serve as a suitable model for non-inflammatory acne and that adapalene treatment decreased open comedones and altered lipid metabolism and cytokine production in these rats.
18 citations
,
January 1990 in “Journal of The American Academy of Dermatology” This study found that dexamethasone effectively suppressed DHEAS levels in women with elevated levels using much lower doses than previously thought, without significant adverse effects.
February 1999 in “Analytical Sciences” A new antiandrogen compound was made and its detailed three-dimensional shape was described.
January 1988 in “Chemical and Pharmaceutical Bulletin” This study found that ointments containing indomethacin and its calcium salt showed potent anti-inflammatory effects on rat paw edema and arthritis with minimal skin irritation, suggesting potential for clinical use.
January 2020 in “International Journal of Research in Pharmacy and Chemistry” This study developed a validated HPLC method for accurately estimating dutasteride and its related compounds in capsules, suitable for routine and stability sample analysis.