January 2013 in “Acta Universitatis Traditionis Medicalis Sinensis Pharmacologiaeque Shanghai” This study found that Huoxue Bushen Mixture was effective in treating female pattern hair loss by improving symptom scores and altering serum hormone levels.
July 2004 in “Transplantation” This study found that enalapril treatment reduced hematocrit levels in posttransplant erythrocytosis patients and increased transferrin saturation index and ferritin levels in those with iron deficiency among long-term renal transplant recipients.
11 citations
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January 2020 in “World Journal of Traditional Chinese Medicine” This study used a glucocorticoid-injection model to mimic kidney-yang deficiency syndrome and reported symptoms related to hormonal imbalances in the hypothalamic-pituitary-target gland axes.
December 2022 in “Journal of The American Academy of Dermatology” The authors maintain there is a significant link between vitamin D deficiency and central centrifugal cicatricial alopecia in Black patients, and call for more research on the topic.
52 citations
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July 2011 in “PubMed” This review discusses the diverse roles of the TRPS1 gene in regulating cartilage, kidney, and hair follicle development, highlighting its functions and interactions, but provides no new experimental results.
4 citations
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December 2019 in “Trials” This study aims to evaluate the effectiveness of YH0618 granules in preventing chemotherapy-induced hair loss in breast cancer patients through a randomized, double-blind, multi-center clinical trial, focusing on potential mechanisms related to kidney deficiency as understood in Chinese Medicine. Results are not yet reported.
January 2025 in “Cancer Cell Research” In this study, the researchers analyzed traditional Chinese medicine treatments for hair loss, concluding that conditions such as liver and kidney deficiencies contribute to alopecia and suggesting herbal treatments like Platycladus orientalis and Polygonum multiflorum for therapy.
August 2024 in “Journal of Contemporary Medical Practice” In this analysis, Professor Ma Shuanquan attributes androgenetic alopecia to liver, spleen, and kidney dysfunctions and describes a treatment approach using Chinese medicines focused on these organs, suggesting individualization and noting significant therapeutic effects.
October 2019 in “Research Square (Research Square)” This study will investigate the efficacy of YH0618 granules on reducing chemotherapy-induced hair loss in breast cancer patients, focusing on potential mechanisms related to kidney deficiency, with outcomes not yet reported.
June 2019 in “Research Square (Research Square)” This study aims to assess the effectiveness of the YH0618 granule in reducing chemotherapy-induced hair loss in breast cancer patients, without disrupting anti-tumor effects, by conducting a randomized, double-blind trial. Results are not reported in the abstract.
January 2019 in “Research Square (Research Square)” In this study, researchers will conduct a randomized, double-blind, multi-center clinical trial to assess the effectiveness of YH0618 granule in preventing chemotherapy-induced hair loss among breast cancer patients, aiming to understand its mechanism related to kidney deficiency in Chinese Medicine. Results are not yet reported.
January 2012 in “Journal of Chengdu University of Traditional Chinese Medicine” This paper discusses Professor WEI Yue-gang's approach to treating androgenetic alopecia with Traditional Chinese Medicine and reports no new clinical results.
17 citations
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January 2020 in “The World Journal of Men's Health” This article discusses the potential health risks associated with long-term use of finasteride and dutasteride for prostate and hair loss treatments, suggesting risks may include non-alcoholic fatty liver disease, insulin resistance, type 2 diabetes, and other metabolic issues.
6 citations
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May 2016 in “Urolithiasis” This study found that the risk of urinary stone disease increased significantly in patients with severe androgenetic alopecia, and that testosterone deficiency was more frequent among these patients.
January 2015 in “Springer eBooks” Chronic kidney disease can cause hair loss, which may be related to zinc deficiency or certain medications, and sometimes hair grows back when the underlying issue is treated.
2 citations
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October 2017 in “PubMed” This study found that serum bone metabolic markers with mild changes are interdependently related to traditional Chinese medicine syndromes in patients with chronic kidney disease-related bone disorders.
October 2023 in “Animal production science” This study investigated how vitamin A deficiency, certain diseases, and pregnancy affect cattle coat hair structure, finding notable keratin fibril interference under vitamin A deficiency and structural modifications in chronic renal failure, while pregnant cows exhibited superior hair tensile strength compared to non-pregnant ones.
April 2026 in “Frontiers in Pharmacology” This review systematically evaluates Erzhi Pill's formulation, therapeutic potential, and challenges, exploring its traditional applications and modern prospects for developing integrated quality control and precise medical strategies.
1 citations
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November 2024 in “AME Medical Journal” In this case study, scurvy was diagnosed in a middle-aged man on hemodialysis with food insecurity and undetectable vitamin C levels, highlighting the diverse risk factors and persistent challenges in managing vitamin C deficiency among patients with complex medical and social issues.
January 2004 in “Journal of Guangzhou University of Traditional Chinese Medicine” This study found that the expression of androgen receptors is higher in the scalp area affected by androgenetic alopecia, and its expression varies based on different traditional Chinese medicine syndromes.
December 2023 in “Journal of nutritional science and vitaminology” This study in mice found that a zinc-deficient diet suppressed body weight gain and increased kidney and cecum tissue weight without decreasing serum alkaline phosphatase activity. Additionally, zinc deficiency caused alopecia and intestinal changes in C57BL/6J mice, potentially affecting nutritional status.
13 citations
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December 2012 in “Frontiers in bioscience” This review discusses the potential role of vitamin D deficiency in cardiovascular and renal diseases and suggests that supplemental vitamin D could benefit cardiovascular outcomes, especially in African American and postmenopausal women; it reports no new clinical findings.
January 2011 in “Liaoning Zhongyiyao Daxue xuebao” This study found that Chinese medicine treatment "Tonifying Kidney and Removing toxins" significantly improved clinical symptoms and reduced disease activity in patients with systemic lupus erythematosus compared to controls.
14 citations
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August 2016 in “Journal of nanomedicine research” This animal study found that biscuits fortified with zinc oxide nanoparticles improved growth, appetite, and hair growth in zinc-deficient rats more effectively than traditional zinc forms, without apparent toxicity.
10 citations
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May 2019 in “International Journal of Environmental Research and Public Health” This study found that finasteride treatment in male rats altered steroid hormone homeostasis and caused kidney damage, suggesting potential risks for patients with renal dysfunction on androgen or antiandrogen therapy.
1 citations
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January 2021 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that loss of the folliculin protein delays transferrin receptor recycling, leading to iron deficiency and suggesting a role in the mechanisms of Birt-Hogg-Dubé syndrome.
29 citations
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June 2015 in “Kidney International” This study developed a kidney-specific knockout mouse model lacking the Flcn gene, which recapitulates human Birt-Hogg-Dubé kidney tumorigenesis and shows that mTOR pathway inhibition with rapamycin can suppress tumor growth.
240 citations
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February 2005 in “Diabetes Care” This review discusses the nutritional and metabolic problems following bariatric surgery, emphasizing the need for ongoing monitoring and treatment, but reports no new clinical results.
27 citations
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November 2000 in “Journal of Veterinary Medicine Series B” This study found that experimentally induced iodine deficiency in growing male lambs led to hypothyroidism, resulting in stunted growth, reduced wool production, and disrupted sexual maturity.
81 citations
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November 2012 in “Journal of the National Cancer Institute” This study found that FLCN deficiency in mice muscles led to increased mitochondrial biogenesis and a metabolic shift towards oxidative phosphorylation, with a similar advantage observed in FLCN-null kidney cancer cells.