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In this double-blind randomized controlled trial, both rosemary extract lotion and 2% ketoconazole lotion were effective for treating scalp seborrheic dermatitis, but rosemary lotion reduced itching more significantly, while ketoconazole was more effective in reducing dandruff.

This study developed a novel antidandruff shampoo with ketoconazole-coated zinc oxide nanoparticles that showed enhanced antifungal activity against Malassezia furfur compared to standard ketoconazole treatments, suggesting it could be a more effective alternative for dandruff management.

Ketoconazole shampoo can cause rare pink hair discoloration.

This study developed a fast and sensitive ultra-high performance liquid chromatography method to quantify ketoconazole in antidandruff emulsions, showing comparable results to labeled concentrations.

This study highlights the potential of a ketoconazole antifungal hair spray as an innovative and effective topical method for treating tinea capitis, offering benefits such as easy application, improved drug penetration, and reduced systemic exposure compared to conventional treatments.

A new microneedle system may improve hair loss treatment by delivering ketoconazole directly to hair follicles.

The study developed herbal shampoo formulations using isolated phytoconstituents, such as eugenol, rutin, menthol, and camphor, which demonstrated similar antifungal efficacy to ketoconazole but with improved safety and detergency, offering a promising alternative for managing seborrheic dermatitis.

This study reports that a novel ketoconazole-loaded microneedle array significantly enhances drug delivery and retention in the skin, demonstrating improved hair growth in animal models, suggesting a promising treatment for androgenic alopecia that addresses current topical therapies' limitations.

Ritlecitinib may help young adults with severe alopecia areata when ketoconazole fails.

Ritlecitinib may help young adults with severe alopecia areata when ketoconazole doesn't work.

Focus on general hair care and lifestyle changes.

Focus on general hair care and lifestyle changes.

In this study, ketoconazole-loaded transferosomes were developed and demonstrated improved hair growth compared to a commercially available ketoconazole product, with the formulation showing enhanced drug penetration and minimal skin irritation in vivo.

This article explores the role of ketoconazole shampoo in hair care beyond treating dandruff and seborrhoeic dermatitis, suggesting it may reduce hair shedding and chronic scalp inflammation, potentially complementing treatments for androgenetic alopecia.

This in-vitro study reported that a luliconazole-based formulation improved hair cuticle integrity and was more effective than ketoconazole in repairing damaged hair after 5 and 10 washes, with sensory analysis supporting these results. Further human studies are needed to confirm its clinical effects.

This study concluded that topical ketoconazole is effective and safe for treating superficial fungal infections and has potential for new dermatologic uses despite concerns over oral administration's adverse effects.

This study found that the new cocrystal formulation KET-PABA improved the antimycotic efficiency of ketoconazole and induced an anti-inflammatory response without causing skin sensitization in mice.

This study analyzed the structure and dynamics of ketoconazole, revealing how its molecular characteristics, such as spin-lattice relaxation time and chemical shift anisotropy, are influenced by π-π stacking interactions and different carbon site environments.

This study found that nisoral treatment in patients with hyperandrogenism was associated with restored menstrual cycles and reduced pathological hair growth, along with decreased testosterone and increased estradiol and progesterone levels.

This study found that combining Chuzhi Shengfa Tablets with either ketoconazole shampoo or 5% minoxidil foam significantly improved hair density, hair diameter, and reduced scalp oil in men with androgenetic alopecia, without increasing adverse reactions.

This review examines the patent literature on AKR1C3 inhibitors and suggests that although numerous potent inhibitors exist, further preclinical optimization is necessary before assessing their therapeutic potential in human diseases.

This study evaluated the effect of 2% ketoconazole lotion for androgenetic alopecia, but the results regarding its effectiveness on clinical appearance remained unclear.

This study identified serum androsterone as a robust biomarker for monitoring response to AKR1C3 inhibitor treatment in women and found that a 4-week administration of aldo-keto reductase 1C3 inhibitors did not impact ovarian function.

This study found that overexpression of AKR1C3 in prostate cancer cells redirected androgen metabolism towards testosterone production, which facilitated cell proliferation, potentially reducing the effectiveness of finasteride treatment.

AKR1B10 enzyme may cause keloid scars and could be a treatment target.

This meeting summary discusses insights from leading dermatologists on scalp management and topical ketoconazole use, but it reports no new research findings.

This meeting summary discusses scalp management and the use of topical ketoconazole in therapeutic hair care, but it reports no new research findings.

This promotional text for True Body Keto highlights its potential benefits for weight loss and suggests it may lower blood sugar, but it reports no new research findings or clinical results.

This review presents European guidelines for treating tinea capitis, noting systemic antifungals are essential, with griseofulvin preferred for Microsporum infections and newer antifungals viable for Trichophyton but often costlier.

In this study, terbinafine reached high concentrations in stratum corneum and sebum after oral administration, with drug levels remaining above fungicidal concentrations for over three weeks.