TLDR Nizoral improved menstrual cycles and reduced hair growth in patients with hyperandrogenism.
The study examined the effects of Nizoral on the hypothalamo-pituitary-ovarian system in 25 patients with hyperandrogenism, with 11 having ovarian and 14 having suprarenal origins. It was found that most patients with oligomenorrhea and anovulation experienced a restoration of the menstrual cycle after 2-3 treatment courses. Additionally, there was a reduction in the rate of pathological hair growth. Nizoral treatment led to decreased testosterone levels, increased estradiol and progesterone levels, unchanged gonadotropins, and reduced urinary excretion of 17-ketosteroids.
March 2022 in “International journal of pharmaceutical sciences review and research” PCOS is a hormonal issue in women that is usually treated with birth control pills, metformin, and lifestyle changes, with early treatment helping to reduce complications and improve life quality.
14 citations
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September 2015 in “Expert Opinion on Therapeutic Targets” The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.
32 citations
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November 1996 in “International Journal of Dermatology” Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.
55 citations
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July 2013 in “Dermatologic therapy” Some dermatological medications can impair male fertility, so consult a doctor before trying to conceive.
7 citations
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December 2019 in “American Journal of Clinical Dermatology” Topical therapies show promise for hair loss and acne treatment with minimal side effects.
