9 citations,
November 2012 in “Biomolecules & therapeutics” A compound from brown algae boosts the production of a certain inflammatory substance in skin cells.
December 2023 in “Revista Urología Colombiana / Colombian Urology Journal” More research is needed to find effective treatments for sickle cell disease-related priapism.
1 citations,
September 2019 in “Journal of Investigative Dermatology” The research showed that CRISPR/Cas9 can fix mutations causing a skin disease in stem cells, which then improved skin grafts in mice, but more work on safety and efficiency is needed.
18 citations,
October 2021 in “Frontiers in Physiology” Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
3 citations,
August 2022 in “JAAD international” Taking a daily multivitamin may be enough to promote hair growth in people with alopecia.
88 citations,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Minoxidil and finasteride effectively treat hair loss.
74 citations,
April 2005 in “Dermatologic Clinics” Minoxidil and finasteride are effective for male hair loss, minoxidil for female hair loss, and various treatments like corticosteroids work for alopecia areata; treatment should be tailored to the individual.
61 citations,
August 2022 in “Journal of Controlled Release” Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.
58 citations,
October 1993 in “International Journal of Dermatology” Minoxidil helps hair growth and reduces shedding in women.
55 citations,
May 2019 in “Journal of Endocrinology” Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.
17 citations,
October 2006 in “Molecular and Cellular Endocrinology” The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.
16 citations,
January 2003 in “Nuclear Receptor Signaling” Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.
11 citations,
March 2021 in “Cleveland Clinic Journal of Medicine” Treating hair loss in both men and women is effective and improves quality of life.
7 citations,
September 2021 in “Antimicrobial Agents and Chemotherapy” Olorofim effectively treats fungal skin infections.
5 citations,
September 2017 in “Plastic and Aesthetic Research” Low dose cyclical nutrition therapy can consistently and safely improve hair growth and density without needing anti-androgens.
5 citations,
December 2023 in “Materials” Organic and biogenic nanocarriers can improve drug delivery but face challenges like consistency and safety.
4 citations,
December 2021 in “Experimental and Therapeutic Medicine” Adult female acne is complex and requires a combination of treatments for effective management.
4 citations,
July 2005 in “International Journal of Dermatology” Topical PUVA and tacrolimus ointment can effectively and safely treat infant alopecia universalis.
3 citations,
January 2019 in “Cureus” Hormonal imbalances in Polycystic Ovarian Syndrome (PCOS) might trigger a rare skin disorder called Confluent and Reticulated Papillomatosis (CRP), so dermatologists should consider checking for PCOS in CRP patients.
3 citations,
November 2010 in “Wiley-VCH Verlag GmbH & Co. KGaA eBooks” Finasteride safely treats enlarged prostate and male-pattern baldness.
2 citations,
July 2022 in “BioMed Research International” Finasteride-loaded nanogels are effective, safe, and improve drug absorption through the skin.
1 citations,
October 2022 in “Journal of dermatological science” Certain vitamins and their derivatives can help hair grow longer by activating specific growth signals.
August 2024 in “Stem Cell Research & Therapy” New regenerative therapies show promise for treating hair loss.
November 2023 in “Clinical, Cosmetic and Investigational Dermatology” Saw palmetto extract reduced hair loss and improved hair growth in people with hair thinning.
June 2023 in “Research journal of topical and cosmetic sciences” The polyherbal lotus oil with amla, hibiscus, bhringraj, and methi promotes hair growth effectively, similar to minoxidil.
June 2015 in “Biomedical and biopharmaceutical research” The congress showed advancements in skin hydration, barrier function, and safe, effective new cosmetic formulations.
April 2023 in “Dermatology and therapy” Most patients stop using topical minoxidil due to side effects.
124 citations,
September 1992 in “Endocrinology” The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.
115 citations,
March 2001 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” Key enzymes control androgen levels, affecting hormone activity and potential treatments.
76 citations,
October 2016 in “Clinics in dermatology” Sex hormones, especially androgens, play a key role in causing acne.