Confluent and Reticulated Papillomatosis Associated with Polycystic Ovarian Syndrome

    January 2019 in “ Cureus ”
    Pallavi Basu, Philip R. Cohen
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    TLDR Hormonal imbalances in Polycystic Ovarian Syndrome (PCOS) might trigger a rare skin disorder called Confluent and Reticulated Papillomatosis (CRP), so dermatologists should consider checking for PCOS in CRP patients.
    In 2019, a study explored the association between Confluent and Reticulated Papillomatosis (CRP), a rare skin disorder, and Polycystic Ovarian Syndrome (PCOS). The research suggested that hormonal imbalances in PCOS could potentially trigger CRP and recommended dermatologists to consider screening for PCOS in patients with CRP. The study was based on a 31-year-old woman with PCOS who presented with CRP. After two months of treatment with azithromycin, her skin condition resolved. The study suggested that CRP might be more common in individuals with PCOS or insulin resistance than previously thought, and that bacterial inoculation might play a role in CRP pathogenesis. However, the study did not provide the number of participants, limiting the strength of its conclusions.
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