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The research shows that hydrogen bonds greatly affect the crystal structure of a Finasteride derivative.

Old drugs like finasteride and spironolactone are being successfully used for hair loss and skin conditions, and many other drugs show promise for new uses in dermatology.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Androstenedione is better than testosterone for diagnosing PCOS in Indian women.

A baby with maple syrup urine disease improved from skin problems by adjusting his diet to correct amino acid levels.

A woman developed severe kidney injury from using simvastatin with ciclosporin, highlighting the need for careful monitoring when combining these drugs.

Women with effluvium have higher levels of certain urinary steroids, possibly due to stress and increased adrenal activity.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Sebocytes play a key role in controlling androgen levels in human skin.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

Myrtle has various health benefits and potential for medicine development.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Laser device increases hair density, safe for treating hair loss in men and women.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Finasteride effectively blocks enzyme causing male pattern baldness.

Fat cells in the skin help start healing and form important repair cells after injury.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.