research Sebaceous Immunobiology: Skin Homeostasis, Innate Immunity Coordination, Inflammatory Response, and Disease Associations
Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
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research Exfoliative Cutaneous Lupus Erythematosus in German Shorthaired Pointer Dogs: Disease Development, Progression, and Evaluation of Three Immunomodulatory Drugs (Ciclosporin, Hydroxychloroquine, and Adalimumab) in a Controlled Environment
Hydroxychloroquine showed some potential, but overall, the three drugs had limited success in treating lupus in dogs.
research Secondary Cicatricial and Other Permanent Alopecias
The document says that treating the root cause of hair follicle damage is crucial to prevent permanent hair loss, and treatment options vary.
research Relating Neurosteroid Modulation of Inhibitory Neurotransmission to Behavior
Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.
research Distribution of Glycolipid and Unsaturated Fatty Acids in Human Hair
Human hair has more unsaturated fats inside than on the surface, and certain lipids may help bind the outer and inner layers together.
research A Review on Steroidal 5α-Reductase Inhibitors for Treatment of Benign Prostatic Hyperplasia
New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.
research Urinary Steroids in Women with Androgenic Alopecia
Women with hair loss had higher levels of certain hormones, suggesting a link to a condition like PCOS.
research A New Label-Free Screen for Steroid 5α-Reductase Inhibitors Using LC-MS
Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.
research Thrombocytosis Associated with Low-Molecular-Weight Heparin
International medical graduates outperformed U.S. graduates on an internal medicine exam.
research Adult Group B Streptococcal Disease
International medical graduates outperformed U.S. graduates on an internal medicine exam.
research Effects of the Anti-Androgen Finasteride on 5α-Reduction of Androgens in the Presence of Progesterone in Human Gingival Fibroblasts: Modulatory Actions of the Alkaline Phosphatase Inhibitor Levamisole
Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.
research Thrombocytopenia and Leukopenia Associated with Itraconazole
Itraconazole may cause low platelet and white blood cell counts.
research The Role of Cytochrome P-450 in Dermatology
Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.
research Love Is in the Hair: Arginine Methylation of Human Hair Proteins as Novel Cardiovascular Biomarkers
Human hair protein modifications could potentially indicate heart disease risk.
research Topical Antiandrogen Therapies for Androgenetic Alopecia and Acne Vulgaris
Topical therapies show promise for hair loss and acne treatment with minimal side effects.
research Safety of Common Medications for Treating Dermatology Disorders in Pregnant Women
Some skin medications are safe for pregnant women, but others pose risks or should not be used.
research Effect of Solvent on Stereoselectivity in Pd/C (Type 39K)-Catalyzed Hydrogenation of Methyl 3-Oxo-4-Aza-5-Androstene-17-Carboxylate, a Key Intermediate for Finasteride and Dutasteride
Alcoholic solvent improves selectivity in key intermediate for finasteride and dutasteride synthesis.
research Androgens in SARS-CoV-2 Coronavirus Infections
Men, particularly those with hair loss, are more likely to get the virus, and those with prostate cancer may have milder symptoms. Testosterone's role in the disease is unclear, and the virus doesn't seem to harm male fertility. Women with PCOS might be at higher risk. More research is needed.
research Anti-Androgen Therapy in Dermatology: A Review
Anti-androgens are effective for female acne but less so for male-pattern hair loss, with side effects similar to birth control pills.
research Alopecia Associated with Fluconazole Therapy
High doses of fluconazole can cause reversible hair loss.
research The First Syntheses of 16β-Chloro- and 16β-Bromo-Cyproterone Acetate
Scientists made two new chemicals that might help treat diseases caused by male hormones.
research Finasteride Inhibits 5α-Reductase Activity in Human Dermal Fibroblasts: Prediction of Its Therapeutic Application in Androgen-Related Skin Diseases
Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.
research Results of 60-Second Timed Hair Counts in Women Aged 20–60 Years
The 60-second timed hair count is a reliable and simple way to measure hair shedding at home, showing older women tend to shed more hair than younger women.
research Hair Cosmetics for the Hair Loss Patient
Proper hair care and safe use of hair products are crucial for those with hair loss.
research Alopecia Areata Is Associated With MICA and an Extended HLA Haplotype
Certain genes are linked to the risk of developing Alopecia Areata.
research Hair Loss in Women: Causes and Treatments
About 40% of women by age 60 experience significant hair loss, often due to androgenetic alopecia, with treatments like minoxidil available and hope for future cures.
research Molecular Docking Studies and ADME-Tox Prediction of Phytocompounds from Punica Granatum Peel as a Potential Anti-Alopecia Treatment
Pomegranate peel compounds may help treat hair loss.
research Androgen Excess: A Hallmark of Polycystic Ovary Syndrome
Excess androgens may cause PCOS, not just be a symptom.
research Hyperandrogenism and Cardiometabolic Risk in Pre- and Postmenopausal Women: What Is the Evidence?
Hyperandrogenism increases heart disease risk in premenopausal women, but this risk is linked to obesity in postmenopausal women.
research Signaling Pathways and Targeted Therapeutic Strategies for Polycystic Ovary Syndrome
Effective PCOS treatments require targeting specific signaling pathways.